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  2. Spike (S) glycoprotein (sometimes also called spike protein, formerly known as E2) is the largest of the four major structural proteins found in coronaviruses. The spike protein assembles into trimers that form large structures, called spikes or peplomers, that project from the surface of the virion.

  3. Jun 14, 2021 · As a predominant focus, coronavirus spike (S) protein plays an essential role in coronavirus infection, pathogenicity, transmission, and evolution. 1 Changes in just a few residues around the spike protein can dramatically affect the infectivity, tropism, and pathogenesis of the virus. 2, 3, 4 Furthermore, potential adaptive mutations in the ...

    • Chaogeng Zhu, Guiyun He, Qinqin Yin, Lin Zeng, Xiangli Ye, Yongzhong Shi, Wei Xu
    • 10.1002/jmv.27132
    • 2021
    • J Med Virol. 2021 Oct; 93(10): 5729-5741.
  4. Aug 17, 2020 · Nature - Cryo-electron microscopy and tomography studies reveal the structures, conformations and distributions of spike protein trimers on intact severe acute respiratory syndrome...

    • Zunlong Ke, Joaquin Oton, Kun Qu, Mirko Cortese, Vojtech Zila, Lesley McKeane, Takanori Nakane, Jase...
    • 2020
  5. Aug 3, 2020 · It is caused by a novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The spike (S) protein of SARS-CoV-2, which plays a key role in the receptor recognition and cell ...

    • Yuan Huang, Chan Yang, Xin feng Xu, Wei Xu, Shu wen Liu
    • 2020
  6. Mar 12, 2020 · 3D print of a spike protein on the surface of SARS-CoV-2—also known as 2019-nCoV, the virus that causes COVID-19. Spike proteins cover the surface of SARS-CoV-2 and enable the virus to enter and infect human cells. For more information, visit the NIH 3D Print Exchange at 3dprint.nih.gov. Credit: NIH. Date.

  7. Spike (S) glycoprotein (sometimes also called spike protein, formerly known as E2) is the largest of the four major structural proteins found in coronaviruses. The spike protein assembles into trimers that form large structures, called spikes or peplomers, that project from the surface of the virion.

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