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  1. Sep 2, 2021 · The main difference between statistical and clinical significance is that the clinical significance observes dissimilarity between the two groups or the two treatment modalities, while statistical significance implies whether there is any mathematical significance to the carried analysis of the results or not.

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  3. Nov 23, 2023 · A key distinction between statistical significance and clinical significance is evident. Statistical significance determines if there is mathematical significance to the analysis of the results. Clinical significance means the difference is vital to the patient and the clinician.

    • Steven Tenny, Ibrahim Abdelgawad
    • 2023/11/23
  4. Feb 14, 2018 · Clinical relevance (also known as clinical significance) indicates whether the results of a study are meaningful or not for several stakeholders. 7 A clinically relevant intervention is the one whose effects are large enough to make the associated costs, inconveniences, and harms worthwhile. 8 Clinical relevance facilitates the understanding ...

    • Susan Armijo-Olivo
    • 2018
  5. Oct 4, 2021 · In the broadest sense, significance refers to the quality of being worthy of attention, of importance, and of having meaning. Three types of significance are reported in the literature: statistical, practical, and clinical. Each has a unique purpose, description, and method of evaluation.

    • Roger Carpenter, Julee Waldrop, Heather Carter-Templeton
    • 2021
  6. May 22, 2024 · - Significance highlights the value of research findings, while clinical significance indicates relevance in terms of positive health or healthcare outcomes. - Consider using “importance” instead of “clinical significance” for discussing effects, as it emphasizes the value of diverse perspectives from patients, families, healthcare ...

    • Christopher Holmberg
  7. Jul 3, 2024 · Clinical Significance is the extent to which a study result is judged to be meaningful in relation to the diagnosis or treatment of disorders. It measures the extent that a change can create a meaningful response for the patient. Understanding Statistical Significance Video 3:29 min. Stastical versus Clinical Significance Video 2:08 min.

  8. Clinical significance is a decision based on the practical value or relevance of a particular treatment, and this may or may not involve statistical significance as an initial criterion. Confidence intervals are one way for researchers to help decide if a particular statistical result (whether significant or not) may be of relevance in practice.

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