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      • Gastrointestinal stromal tumors are tumors of the gastrointestinal tract derived from mesenchymal precursor cells in the gut wall (interstitial cells of Cajal). Diagnosis is usually by endoscopy. Treatment is surgical removal.
      www.merckmanuals.com › professional › gastrointestinal-disorders
  1. Apr 27, 2023 · Targeted drug therapy for GISTs often begins with imatinib (Gleevec). Targeted drug treatments can be given: After surgery to lower the risk that the cancer will come back; Before surgery to shrink the tumor and make it easier to remove; As the first treatment if the cancer has spread to other parts of the body; If the GIST comes back; Other ...

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  3. Jul 17, 2024 · A gastrointestinal stromal tumor is a type of sarcoma that develops in the connective tissue of the gastrointestinal tract. It’s often referred to as GIST. GISTs are usually found in adults between the ages of 30 and 50. Though rare, GISTs can also be found in children and young adults.

  4. Aug 28, 2020 · Gastrointestinal stromal tumors (GIST) are usually found on the stomach or small intestine, but they can be found anywhere in or near the GI tract. Find out about risk factors, symptoms, tests to diagnose, prognosis, staging, and treatment for gastrointestinal stromal tumors.

  5. May 28, 2020 · This page lists cancer drugs approved by the Food and Drug Administration (FDA) for gastrointestinal stromal tumors (GIST). The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  6. This treatment uses drugs designed to target specific components of cancer cells that are not found in healthy cells. GISTs are treated with targeted drugs called tyrosine kinase inhibitors (TKIs). Several types of TKIs are available, including imatinib, sunitinib, regorafenib, and avapritinib, among others.

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    • define gist tumor in humans treatment drugs information form1
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  7. Targeted therapy drugs called tyrosine kinase inhibitors (TKIs) are used to treat GISTs. TKIs are taken by mouth in pill form. TKIs may be used if: The tumor can’t be safely removed with surgery or only part of it can be removed. The cancer has spread from the initial site. The cancer has come back after treatment. The risk of recurrence is high.

  8. May 11, 2023 · Gastrointestinal stromal tumors (GISTs) treatment depends on the extent of disease and may involve surgery and/or tyrosine kinase inhibitors. Get detailed information about the diagnosis, prognosis, and treatment of newly diagnosed and recurrent GISTs in this summary for clinicians.

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