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      • Gastrointestinal stromal tumors are tumors of the gastrointestinal tract derived from mesenchymal precursor cells in the gut wall (interstitial cells of Cajal). Diagnosis is usually by endoscopy. Treatment is surgical removal.
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  1. Apr 27, 2023 · For GISTs, the target of these drugs is an enzyme called tyrosine kinase that helps cancer cells grow. Targeted drug therapy for GISTs often begins with imatinib (Gleevec). Targeted drug treatments can be given: After surgery to lower the risk that the cancer will come back; Before surgery to shrink the tumor and make it easier to remove; As ...

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  3. Jul 17, 2024 · A gastrointestinal stromal tumor, also called a GIST, is a type of sarcoma that develops in the connective tissue of the gastrointestinal tract. Sarcoma medical oncologist Neeta Somaiah, M.D., shares how this cancer develops, how it’s treated and if it’s curable.

  4. Aug 28, 2020 · Gastrointestinal stromal tumors (GIST) are usually found on the stomach or small intestine, but they can be found anywhere in or near the GI tract. Find out about risk factors, symptoms, tests to diagnose, prognosis, staging, and treatment for gastrointestinal stromal tumors.

  5. May 11, 2023 · Gastrointestinal stromal tumors (GISTs) treatment depends on the extent of disease and may involve surgery and/or tyrosine kinase inhibitors. Get detailed information about the diagnosis, prognosis, and treatment of newly diagnosed and recurrent GISTs in this summary for clinicians.

  6. May 28, 2020 · This page lists cancer drugs approved by the Food and Drug Administration (FDA) for gastrointestinal stromal tumors (GIST). The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  7. A gastrointestinal stromal tumor (GIST) is a rare type of cancer in which abnormal cells form in the gastrointestinal (digestive) tract. Also called the GI tract, the gastrointestinal tract is the passageway between the mouth and the anus, which includes the organs responsible for breaking down food and absorbing nutrients.

  8. Surgery is not typically the first treatment for these tumors, so before starting treatment, it’s important to confirm that the tumor is in fact a GIST with a biopsy. The targeted drug imatinib (Gleevec) is typically the preferred first treatment for most advanced GISTs.

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