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1. • • For GISTs that have not spread to other parts of the body, surgery is used to remove all of the cancer. Sometimes, targeted therapy is used to shrink the tumor (s) before surgery. Targeted therapy is also used to treat GISTs that are advanced or have spread to other parts of the body. The drugs used are oral tyrosine kinase inhibitors.
     www.mdanderson.org › cancerwise › gastrointestinal-stromal-tumors--gists---what-are-they-and-how-are-they-treated

     Gastrointestinal stromal tumors (GISTs): What are they, and ...

2. www.cancer.gov › about-cancer › treatmentDrugs Approved for Gastrointestinal Stromal Tumors - NCI

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   May 28, 2020 · This page lists cancer drugs approved by the Food and Drug Administration (FDA) for gastrointestinal stromal tumors (GIST). The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

3. People also ask

   Can a gist start as one tumor?

   • They often start as one tumor. In rare cases, people can be prone to developing multiple tumors at a younger age, or multiple family members can have a GIST. This usually happens in patients who have certain inherited mutations in the KIT, PDGFRA or SDH genes, or have the inherited disorder neurofibromatosis type 1.

   Gastrointestinal stromal tumors (GISTs): What are they, and how are

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   What causes a GIST tumor?

   • Most GISTs arise because of a random mutation in a cell’s KIT or PDGFR gene that occurs sporadically, meaning there’s no known cause. They often start as one tumor. In rare cases, people can be prone to developing multiple tumors at a younger age, or multiple family members can have a GIST.

   Gastrointestinal stromal tumors (GISTs): What are they, and how are

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   What is the first treatment for a GIST tumor?

   • Surgery is not typically the first treatment for these tumors, so before starting treatment, it’s important to confirm that the tumor is in fact a GIST with a biopsy . The targeted drug imatinib (Gleevec) is typically the preferred first treatment for most advanced GISTs.

   Typical Treatment Options for Gastrointestinal Stromal Tumors

   www.cancer.org/cancer/types/gastrointestinal-stromal-tumor/treating/by-spread.html

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   What is a gist & how does it work?

   • A GIST is a growth of cells that's thought to form from a special type of nerve cells. These special nerve cells are in the walls of the digestive organs. They play a part in the process that moves food through the body. Small GIST s may cause no symptoms, and they may grow so slowly that they don't cause problems at first.

   Gastrointestinal stromal tumor (GIST) - Overview - Mayo Clinic

   www.mayoclinic.org/diseases-conditions/gastrointestinal-stromal-tumors/cdc-20387715

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4. www.mayoclinic.org › diseases-conditionsGastrointestinal stromal tumor (GIST) - Overview - Mayo Clinic

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   Apr 27, 2023 · For GISTs, the target of these drugs is an enzyme called tyrosine kinase that helps cancer cells grow. Targeted drug therapy for GISTs often begins with imatinib (Gleevec). Targeted drug treatments can be given: After surgery to lower the risk that the cancer will come back; Before surgery to shrink the tumor and make it easier to remove; As ...

5. www.mdanderson.org › cancerwise › gastrointestinalGastrointestinal stromal tumors (GISTs): What are they, and ...

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   Jul 17, 2024 · A gastrointestinal stromal tumor is a type of sarcoma that develops in the connective tissue of the gastrointestinal tract. It’s often referred to as GIST. GISTs are usually found in adults between the ages of 30 and 50. Though rare, GISTs can also be found in children and young adults.

6. www.cancer.gov › patient › gist-treatment-pdqGastrointestinal Stromal Tumors Treatment - NCI

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   Aug 28, 2020 · Gastrointestinal stromal tumors (GIST) are usually found on the stomach or small intestine, but they can be found anywhere in or near the GI tract. Find out about risk factors, symptoms, tests to diagnose, prognosis, staging, and treatment for gastrointestinal stromal tumors.

7. www.cancer.gov › hp › gist-treatment-pdqGastrointestinal Stromal Tumors Treatment (PDQ®) - NCI

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   May 11, 2023 · Gastrointestinal stromal tumors (GISTs) treatment depends on the extent of disease and may involve surgery and/or tyrosine kinase inhibitors. Get detailed information about the diagnosis, prognosis, and treatment of newly diagnosed and recurrent GISTs in this summary for clinicians.

8. www.onkopedia-guidelines.info › en › onkopediaGastrointestinal stromal tumors (GIST)

   www.onkopedia-guidelines.info › en › onkopedia

   Gastrointestinal stromal tumors (GIST) Recommendations from the society for diagnosis and therapy of haematological and oncological diseases. Publisher. DGHO Deutsche Gesellschaft für Hämatologie und Medizinische Onkologie e.V. Bauhofstr. 12 D-10117 Berlin. Executive chairman: Prof. Dr. med. Andreas Hochhaus. Phone: +49 (0)30 27 87 60 89 - 0.

9. www.cancer.org › cancer › typesTypical Treatment Options for Gastrointestinal Stromal Tumors

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   Surgery is not typically the first treatment for these tumors, so before starting treatment, it’s important to confirm that the tumor is in fact a GIST with a biopsy. The targeted drug imatinib (Gleevec) is typically the preferred first treatment for most advanced GISTs.