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May 11, 2023 · Gastrointestinal stromal tumors (GISTs) treatment depends on the extent of disease and may involve surgery and/or tyrosine kinase inhibitors. Get detailed information about the diagnosis, prognosis, and treatment of newly diagnosed and recurrent GISTs in this summary for clinicians.
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May 28, 2020 · This page lists cancer drugs approved by the Food and Drug Administration (FDA) for gastrointestinal stromal tumors (GIST). The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.
Aug 28, 2020 · Gastrointestinal stromal tumor is a disease in which abnormal cells form in the tissues of the gastrointestinal tract. Genetic factors can increase the risk of having a gastrointestinal stromal tumor. Signs of gastrointestinal stromal tumors include blood in the stool or vomit.
In resectable GIST, treatment is multimodal. For tumors with a high risk of recurrence, as deter mined by tumor size and mitotic rate, adjuvant therapy with imatinib is indicated. In metastatic disease, systemic drug therapy is the treatment of choice.
Sep 26, 2022 · Gastrointestinal stromal tumors (GISTs) are typically benign tumors that most commonly occur in the gastrointestinal (GI) tract. While only comprising 0.1% to 3% of all GI malignancies, these tumors are the most common mesenchymal tumors of the GI tract.
- Jacob Burch, Iftiker Ahmad
- 2022/09/26
- 2020
Aug 20, 2018 · The approaches to treating GISTs are to resect primary low-risk tumors, resect high-risk primary or metastatic tumors with imatinib 400 mg daily for 12 months, or if the tumor is unresectable, neoadjuvant imatinib 400 mg daily followed by surgical resection is recommended.
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Surgery is not typically the first treatment for these tumors, so before starting treatment, it’s important to confirm that the tumor is in fact a GIST with a biopsy. The targeted drug imatinib (Gleevec) is typically the preferred first treatment for most advanced GISTs.
