Search results
In patients with coronary disease, two studies have shown that ACE inhibitors prevent tolerance after 24 to 48 h of continuous nitroglycerin use, with an increase in cardiac index and reductions in systemic vascular resistance, arterial pressure, and pulmonary wedge pressure (18,55).
- Divya Gupta, Vasiliki V. Georgiopoulou, Andreas P. Kalogeropoulos, Catherine N. Marti, Clyde W. Yanc...
- 2013
May 17, 2011 · Through the same hemodynamic effects, organic nitrates also markedly improve left ventricular function in patients with congestive heart failure, decreasing right atrial pressure with a redistribution of blood from the central circulation into larger capacitance veins, a reduction in impedance to the left ventricle ejection owing to an increase ...
Searches related to define major glass defect in heart disease treatment nitrate reduction
Aug 6, 2013 · To quantify the effect of different nitrate preparations (isosorbide dinitrate and nitroglycerin) and the effect of route of administration of nitrates on clinical outcome, and to evaluate the safety and tolerability of nitrates in the management of AHFS. Search methods.
- Abel Wakai, Aileen McCabe, Rachel Kidney, Steven C Brooks, Rawle A Seupaul, Deborah B Diercks, Nigel...
- 10.1002/14651858.CD005151.pub2
- 2013
- 2013/08
Apr 4, 2017 · Nitrates may be beneficial in heart failure with preserved ejection fraction (HFpEF) by enhancing cGMP signaling and improving hemodynamics, but real-world data on potential efficacy are lacking.
- Shir Lynn Lim, Lina Benson, Ulf Dahlström, Carolyn S.P. Lam, Lars H. Lund
- 2017
www.uptodate.com · contents · nitrates-in-theNitrates in the management of chronic coronary syndrome
Oct 17, 2023 · While they act as venodilators, coronary vasodilators, and modest arteriolar dilators, the primary antiischemic effect of nitrates is to decrease myocardial oxygen demand by producing systemic vasodilation more than coronary vasodilation.
This study aimed to investigate whether nitrate use increased the risk of cardiovascular events in patients with HFpEF. The present study is not a prespecified secondary analysis of the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) trial data.
People also ask
Does nitrate affect activity tolerance in heart failure?
Are nitrates effective in heart failure with preserved ejection fraction (HFpEF)?
Is long-term nitrate use deleterious in ischemic heart disease?
www.ncbi.nlm.nih.gov · pmc · articlesNitrates as an Integral Part of Optimal Medical Therapy and ...
Apr 23, 2012 · The use of short‐ and rapidly‐acting nitrates (eg, sublingual nitroglycerin spray and tablets) is at the core of the therapeutic armamentarium and should be integrated into optimal medical therapy for stable angina along with exercise therapy.
