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1. www.mayoclinicproceedings.org · article · S0025-6196Use of Nitrates and Risk of Cardiovascular Events in Patients ...

   www.mayoclinicproceedings.org · article · S0025-6196

   

   This study aimed to investigate whether nitrate use increased the risk of cardiovascular events in patients with HFpEF. The present study is not a prespecified secondary analysis of the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) trial data.

2. www.ahajournals.org · doi · 10Nitrate Therapy | Circulation - AHA/ASA Journals

   www.ahajournals.org · doi · 10

   

   May 17, 2011 · Heitzer T, Just H, Brockhoff C, Meinertz T, Olschewski M, Munzel T. Long-term nitroglycerin treatment is associated with supersensitivity to vasoconstrictors in men with stable coronary artery disease: prevention by concomitant treatment with captopril.

3. www.ncbi.nlm.nih.gov · pmc · articlesNitrates as an Integral Part of Optimal Medical Therapy and ...

   www.ncbi.nlm.nih.gov · pmc · articles

   

   Apr 23, 2012 · The use of short‐ and rapidly‐acting nitrates (eg, sublingual nitroglycerin spray and tablets) is at the core of the therapeutic armamentarium and should be integrated into optimal medical therapy for stable angina along with exercise therapy.

   • Author: William E. Boden, Aloke V. Finn, Dharmesh Patel, W. Frank Peacock, Udho Thadani, Franklin H. Zimmerm...
   • DOI: 10.1002/clc.21993

   • Publish Year: 2012
   • Publication: Clin Cardiol. 2012 May; 35(5): 263-271.

4. www.ahajournals.org · doi · fullAssociation Between Use of Long-Acting Nitrates and Outcomes ...

   www.ahajournals.org · doi · full

   

   Apr 4, 2017 · Nitrates may be beneficial in heart failure with preserved ejection fraction (HFpEF) by enhancing cGMP signaling and improving hemodynamics, but real-world data on potential efficacy are lacking.

   • Author: Shir Lynn Lim, Lina Benson, Ulf Dahlström, Carolyn S.P. Lam, Lars H. Lund

   • Publish Year: 2017

5. www.aafp.org · pubs · afpStable Coronary Artery Disease: Treatment | AAFP

   www.aafp.org · pubs · afp

   

   Mar 15, 2018 · Patients with angina whose symptoms are not controlled with beta blockers or calcium channel blockers can use long-acting nitrates; short-acting nitrates can be used for quick relief of...

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6. www.texasheart.org · topics · nitratesNitrates - The Texas Heart Institute

   www.texasheart.org · topics · nitrates

   

   Nitrates are used to treat the chest pain associated with angina and to ease the symptoms of congestive heart failure (CHF). How do nitrates work? Nitrates are a vasodilator. Vasodilators widen (dilate) the blood vessels, improving blood flow and allowing more oxygen-rich blood to reach the heart muscle.

7. People also ask

   What nitrates should be used for stable angina?

   • The use of short‐ and rapidly‐acting nitrates (eg, sublingual nitroglycerin spray and tablets) is at the core of the therapeutic armamentarium and should be integrated into optimal medical therapy for stable angina along with exercise therapy.

   Nitrates in Optimal Medical Therapy - National Center for Biotechnology

   www.ncbi.nlm.nih.gov/pmc/articles/PMC6652630/

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   Does nitrate use affect cardiovascular events in patients with HFpEF?

   • The association of nitrate use with the occurrence of cardiovascular events in patients with HFpEF was assessed in a subset of patients included in the TOPCAT trial. 11 The National Heart, Lung, and Blood Institute approved the use of patient data.

   Use of Nitrates and Risk of Cardiovascular Events in Patients With

   www.mayoclinicproceedings.org/article/S0025-6196(19)30046-1/fulltext

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   Are nitrates effective in heart failure with preserved ejection fraction (HFpEF)?

   • Nitrates may be beneficial in heart failure with preserved ejection fraction (HFpEF) by enhancing cGMP signaling and improving hemodynamics, but real-world data on potential efficacy are lacking.

   Association Between Use of Long-Acting Nitrates and Outcomes in Heart

   www.ahajournals.org/doi/full/10.1161/circheartfailure.116.003534

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   Does nitrate cause a loss of hemodynamic effect in congestive heart failure?

   • In congestive heart failure, it has been described as the loss of hemodynamic effect of the administered nitrate, 34 and in hypertension, it is evident as the rapid loss of the hypotensive effects of these drugs. Rather controversial data have been reported for the antiplatelet effects of GTN.

   Nitrate Therapy | Circulation - AHA/ASA Journals

   www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.110.981407

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8. www.jacc.org · doi · 10Nitrate Therapy for Heart Failure: Benefits and Strategies to ...

   www.jacc.org · doi · 10

   

   Demonstrating similar clinical benefits with nitrates plus angiotensin-converting enzyme inhibitor therapy alone, in the absence of hydralazine, may represent an opportunity to improve heart failure care by increasing the use of nitrates. In this paper, we summarize data that support studying such an approach.