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Nov 23, 2022 · Cardiac muscle fibers are long, branched cells, shaped like cylinders joined end-to-end, with one or two nuclei located centrally. The fibers are separated by collagenous tissue that supports the capillary network of cardiac tissue. The myofilaments of cardiac muscle are arranged in a similar pattern to skeletal muscle, resulting in cross ...
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A desmosome is a cell structure that anchors the ends of cardiac muscle fibers together so the cells do not pull apart during the stress of individual fibers contracting ([link]). Cardiac Muscle. Intercalated discs are part of the cardiac muscle sarcolemma and they contain gap junctions and desmosomes.
- OpenStaxCollege
- 2013
- Dilated Cardiomyopathy
- Hypertrophic Cardiomyopathy
- Restrictive Cardiomyopathy
- Arrhythmogenic Right Ventricular Dysplasia
- Transthyretin Amyloid Cardiomyopathy
Dilated cardiomyopathy causes the cardiac muscle tissue of the left ventricle to stretch and the heart’s chambers to dilate.
Hypertrophic cardiomyopathy (HCM) is a genetic condition in which the cardiomyocytes are not arranged in a coordinated fashion and are instead disorganized. HCM can interrupt blood flow out of the ventricles, cause arrhythmias (abnormal electrical rhythms), or lead to congestive heart failure.
Restrictive cardiomyopathy (RCM) refers to when the walls of the ventricles become stiff. When this happens, the ventricles cannot relax enough to fill with an adequate amount of blood.
This rare form of cardiomyopathy causes fatty infiltration in cardiac muscle tissue in the right ventricle.
Transthyretin amyloid cardiomyopathy (ATTR-CM) develops when amyloid proteins collect and form deposits in the walls of the left ventricle. The amyloid deposits cause the ventricle’s walls to stiffen, which prevents the ventricle from filling with blood and reduces its ability to pump blood out of the heart. This is a form of RCM.
Sep 2, 2023 · Myocardial Tissue Detail. At a cellular level, heart muscle tissue is made up of bundles or fibers of interconnected muscle cells, called cardiomyocytes. These cells are packed with units called sarcomeres that are made of proteins called actin and myosin.
Cardiac muscle cells (also called cardiomyocytes) are the contractile myocytes of the cardiac muscle. The cells are surrounded by an extracellular matrix produced by supporting fibroblast cells. Specialised modified cardiomyocytes known as pacemaker cells, set the rhythm of the heart contractions.
Aug 8, 2023 · Cardiac muscle (or myocardium) makes up the thick middle layer of the heart. It is one of three types of muscle in the body, along with skeletal and smooth muscle. The myocardium is surrounded by a thin outer layer called the epicardium (AKA visceral pericardium) and an inner endocardium.
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Feb 24, 2023 · However, cardiac muscle fibers are shorter than skeletal muscle fibers and usually contain only one nucleus, which is located in the central region of the cell. Cardiac muscle fibers also possess many mitochondria and myoglobin, as ATP is produced primarily through aerobic metabolism.
