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  1. Sep 26, 2022 · Gastrointestinal stromal tumors (GISTs) are a group of rare tumors that can occur anywhere along the digestive tract, but most commonly occur in the stomach or small intestine. GISTs most commonly occur later in life but can occur at any age. The average age at diagnosis is in the 60s.

    • Jacob Burch, Iftiker Ahmad
    • 2022/09/26
    • 2020
  2. Aug 20, 2018 · Gastrointestinal stromal tumors (GISTs) were originally believed to have originated from the mesenchymal cells of the gastrointestinal tract (GIT) ( 1, 2 ). Kindblom and associates in 1998 found that these tumors actually originate from the interstitial cells of Cajal ( 3 ).

    • Trisha M. Parab, Michael J. DeRogatis, Alexander M. Boaz, Salvatore A. Grasso, Paul S. Issack, David...
    • 10.21037/jgo.2018.08.20
    • 2018
    • 2019/02
  3. Aug 24, 2023 · Gastrointestinal stromal tumor (GIST) is the most common malignant neoplasm of mesenchymal origin. GIST spans a wide clinical spectrum that ranges from tumors with essentially no metastatic potential to malignant and life-threatening spread diseases.

    • 10.1177/17588359231192388
    • 2023
  4. Oct 16, 2019 · pp 817–849. Cite this chapter. Download book PDF. Download book EPUB. International Manual of Oncology Practice. Attila Kollár, Pedro Nazareth Aguiar Jr., Nora Manoukian Forones & Ramon Andrade De Mello. 805 Accesses. Abstract. Gastrointestinal stromal tumor is the most common mesenchymal neoplasm arising the gastrointestinal tract.

    • Attila Kollàr
    • 2015
  5. incidence. Gastrointestinal stromal tumors (GISTs) are rare tumors, with an estimated incidence of 1.5/100 000/year (unadjusted data) [ 1. ]. This only covers the clinically relevant GISTs, since likely a much higher number of microscopic lesions could be found pathologically, if looked for. The median age is around 60–65 years, with a wide range.

  6. Download book EPUB. Overview. Editors: Yukinori Kurokawa, Yoshito Komatsu. Enriches our understanding of GISTs both from basic to clinical aspects. Collects unique and cutting-edge data from the Asian region. Provides a comprehensive update of GISTs. 4875 Accesses. 2 Citations. About this book.

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  8. Apr 11, 2023 · Most GISTs harbor characteristic mutations in KIT or platelet-derived growth factor receptor alpha (PDGFRA), while mutations in succinate dehydrogenase (SDH) or other genes are less frequent. The clinical presentation, diagnosis, and prognosis of GISTs will be discussed here.