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Discovery of antibacterial activity. Confirmation. Zephirol. Cancer therapy. Nobel Prize and issues. Awards and honours. References. External links. Gerhard Domagk. Gerhard Johannes Paul Domagk ( German pronunciation: [ˈɡeːɐ̯haʁt ˈdoːmak] ⓘ; 30 October 1895 – 24 April 1964) was a German pathologist and bacteriologist .
Introduced in 1935 by Gerhard Domagk (1895–1964), sulfa drugs, or sulfonamides, all of which are related to the compound sulfanilamide, provided the first successful therapies for many bacterial diseases.
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Apr 20, 2024 · Gerhard Domagk was a German bacteriologist and pathologist who was awarded the 1939 Nobel Prize for Physiology or Medicine for his discovery (announced in 1932) of the antibacterial effects of Prontosil, the first of the sulfonamide drugs. Domagk earned a medical degree from the University of Kiel
- The Editors of Encyclopaedia Britannica
Gerhard Domagk (1895–1964) was awarded the Nobel Prize in Medicine in 1939 for his work with prontosil and sulfanilamide, the active breakdown product of prontosil in the body. Sulfanilamide, the first synthetic antimicrobial created, served as the foundation for the chemical development of a family of sulfa drugs.
Abstract. Examines the life and contributions of Gerhard Domagk , who discovered the curative effects of two important drugs and winner of the 1939 Nobel Prize for medicine. KEYWORDS (Audience): General Public. KEYWORDS (Domain): History / Philosophy. KEYWORDS (Subject): Medicinal Chemistry. Cited By. This article is cited by 2 publications.
- Ralph E. Oesper
- 1954
May 21, 2018 · His paper “Ein Beitrag zur Chemotherapie der bakteriellen Infektionen” has become not only a classic but—measured by strict experimental and statistical yardsticks—a masterpiece of careful and critical evaluation of a new therapeutic agent.
The discovery of the antibacterial action of the sulphonamides was not, however, Domagk's only contribution to chemotherapy. He also discovered the therapeutic value of the quaternary ammonium bases and he also extended, in collaboration with Klarer and Mietzsch, his work on the sulphonamides.
