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  2. Jul 15, 2022 · For men and people assigned male at birth (AMAB), germ cells mature into sperm. Related, germ cell tumors most often form where eggs get made (ovaries) and where sperm gets made (testicles). Less commonly, germ cell tumors form in body parts other than your ovaries and testicles, including your abdomen, chest, low back, tailbone and brain.

  3. Dec 1, 2022 · Germ cell cancer can develop in the testicles or ovaries, or in other parts of the body. Learn about the different types, symptoms, causes, and treatment options for this rare cancer.

    • Daniel Yetman
  4. Jun 6, 2023 · Overview. Germ cell tumors are growths of cells that form from reproductive cells. The tumors may be cancerous or not cancerous. Most germ cell tumors occur in the testicles or the ovaries. Some germ cell tumors occur in other areas of the body, such as the abdomen, brain and chest, though it's not clear why.

  5. Types of testicular tumors. About 95 out of every 100 testicular cancers start in germ cells. These are cells in the testicles that make sperm. These tumors often start in the testicles. But they also can start in the abdomen (belly), chest, or other areas of the body.

  6. Dec 3, 2021 · Key Points. Extragonadal germ cell tumors form from developing sperm or egg cells that travel from the gonads to other parts of the body. Age and gender can affect the risk of extragonadal germ cell tumors. Signs and symptoms of extragonadal germ cell tumors include breathing problems and chest pain.

  7. Oct 1, 2021 · Abstract. Testicular germ cell tumors (TGCTs) demonstrate a wide variety of histopathologic, genetic, pathogenetic, and immunocytochemical characteristics and various clinical-biologic profiles and prognoses.

  8. Mar 15, 2024 · Most testicular cancers are germ cell tumors. For treatment planning, germ cell tumors are broadly divided into seminomas and nonseminomas because they have different prognostic and treatment algorithms. For patients with seminomas (all stages combined), the cure rate exceeds 90%.

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