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  1. The Mark of Cain Removal Spell is a very powerful spell which can remove the Mark of Cain from someone. It was written down in the Book of the Damned by Agnes. After Dean Winchester took on the Mark of Cain to kill Abaddon and slaughtered a group of human criminals, his brother Sam began looking...

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  3. May 9, 2024 · After Cain was trapped, the two bearers of the Mark faced off in a fight to the death which Dean won, killing Cain who claimed that there was no cure for the Mark. Following his killing of Cain, the Mark's influence on Dean grew even stronger, nearly being completely consumed by its power.

  4. The Mark was able to corrupt both Lucifer and Cain, despite the former being a powerful archangel, and turned Dean into a demon before it was removed. However, at least in Lucifer's case, the Mark simply made him more of what he already was, as, according to God, he never liked humans.

  5. May 21, 2015 · Death tells Dean that, thanks to the Mark of Cain, killing Dean is impossible. However, it is possible to get rid of the Mark. And here’s where we get to the fun stuff.

    • Samantha Highfill
  6. In the episode, Dean kills a hunter and decides to summon Death to help him with the Mark of Cain as Sam tries to stop him. Meanwhile, Castiel and Crowley meet with Rowena in an attempt to destroy the Mark of Cain.

  7. May 19, 2015 · AT DEATH’S WILL | The key to Dean’s survival may lie in the return of Death, who can remove the Mark of Cain — on “a fairly sizable, non-negotiable condition,” he offers in the promo ...

  8. Apr 30, 2024 · Dean approaches Cain with the First Blade, but Cain easily rebuffs Dean's advances. He knows that Dean is holding back because Dean believes he can control the darkness if he doesn't let it all out. Cain knocks Dean down and then tells Dean that there is no beating the Mark.

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