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  1. Aug 1, 2023 · The lethal dose of alcohol is about 5 to 8 grams per kilogram of body weight (g/kg). BAC refers to the amount of alcohol in the bloodstream. If a person has a 0.20% BAC, that means the blood contains two parts of alcohol per 2,000 parts blood. The legal intoxication level of alcohol is 0.08% BAC.

  2. The value of LD 50 for a substance is the dose required to kill half the members of a tested population after a specified test duration. LD 50 figures are frequently used as a general indicator of a substance's acute toxicity. A lower LD 50 is indicative of higher toxicity.

    Substance
    Animal, Route
    Ld50 {lc50}
    Ld50 : G/kg {lc50 : G/l} ...
    Water (H2O)
    rat, oral
    >90,000 mg/kg
    >90
    Sucrose (table sugar)
    rat, oral
    29,700 mg/kg
    29.7
    rat, oral
    25,800 mg/kg
    25.8
    Glucose (blood sugar)
    rat, oral
    25,800 mg/kg
    25.8
  3. This online calculator will give the known LD50 (median lethal dose) value of Ethanol given any mass. LD50 is measured in units of mg/kg and represents the amount of a substance necessary to have lethal consequences in half of the affected population...

  4. Jul 27, 2014 · As a final note, the graphic provides the LD50 values for water, caffeine and alcohol (ethanol). It’s worth noting that, in the case of caffeine, drinking 118 cups of coffee would almost certainly see you dying of water poisoning before caffeine poisoning!

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  5. Feb 11, 2018 · Specifically, the LD50 represents the dose at which a substance is lethal for 50% of tested subjects. This value is then used as an indicator of a substance’s relative toxicity. Thus, a substance with a high LD50 would have a low toxicity, while a substance with a low LD50 would have a high toxicity. This information is highly useful when ...

  6. May 10, 2024 · As a part of the information in Safety Data Sheets. Remember, the LD 50 is only a estimate so that lethal toxicity can be compared. It says nothing about levels at which other acute toxic, but non-lethal, effects might occur. The LD 50 is only one source of toxicity information. For a more thorough picture of the immediate or acute toxicity of ...

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  8. Jan 30, 2015 · The methodology was based on comparing the “therapeutic index” of the substances, which was defined as the ratio of the median lethal dose (LD50) to the median effective dose (ED50). The results were expressed in a qualitative score as safety margin from “very small” (e.g. heroin) to “very large” (e.g. cannabis).

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