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  2. Mar 30, 2019 · About 5 to 10 percent of all ALS patients appear to have a genetic or inherited component. In those families, 50 percent of the all offspring are expected to have the disease. Most who develop ALS ...

    • Healthcentral
  3. Jul 29, 2019 · Also known as Lou Gehrig’s disease, ALS is a condition that kills off motor neurons, which are crucial to all physical tasks, from brushing one’s hair to breathing. The root cause behind every case is not always the same; there’s a slew of genetic factors that play into the onset of ALS. Yet one gene is often the culprit.

  4. Dec 18, 2023 · Amyotrophic lateral sclerosis (ALS) is a degenerative disease that affects the brain and spinal cord. It causes a worsening loss of voluntary muscle control affecting movements like talking ...

  5. A small percentage of people inherit the disease. Risk Factors. Risk factors that could contribute to Lou Gehrig’s disease include: Age: Lou Gehrig’s disease usually occurs in people between ages 40 and 70. Being male: In cases diagnosed before age 65, more men than women have the condition. Heredity: About 10 percent of cases are inherited ...

  6. Dec 16, 2022 · A mutation of a gene called SOD1 has been identified in some of the hereditary cases, but we do not know what role the mutation plays in the disease. Using an evidence-based approach, smoking was found to be more likely than not a risk factor for ALS based on two excellent studies by Kamel, et al., and Nelson, et al. Smoking has a broad public ...

  7. The disease was identified in 1869 by French neurologist Jean-Martin Charcot and became more widely known internationally on June 2, 1941, when it ended the career of one of baseball’s most beloved players, Lou Gehrig. For many years, ALS was commonly known as Lou Gehrig’s disease. Gehrig played with the New York Yankees for 17 years and ...

  8. Formally known as amyotrophic lateral sclerosis (ALS), Lou Gehrig's disease usually strikes people in their 40s or 50s. Neurons in the brain and spinal cord that control muscles degenerate, eventually killing those affected. The cause of most ALS cases remains a mystery, but about 10% are inherited, and in 1993, scientists found that a gene ...

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