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- Most Merkel cell tumors in dogs are benign.
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Most Merkel cell tumors in dogs are benign. In contrast, Merkel cell carcinoma in cats is associated with a poor prognosis, with frequent occurrence of metastasis to regional lymph nodes and distant organs.
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Jan 16, 2021 · Merkel cell carcinoma (MCC) is in humans and cats a malignant cutaneous neuroendocrine carcinoma, whereas in dogs it possibly has a more benign behaviour. It may be cytologically confused with round cell tumours such as lymphoma because of its striking cytomorphologic similarity.
- Francine E M M van der Steen, Guy C M Grinwis, Erik A W S Weerts, Erik Teske
- 10.1111/vco.12672
- 2021
- Vet Comp Oncol. 2021 Jun; 19(2): 393-398.
- Malignant Lymphoma. Malignant lymphoma is one of the most common types of cancer that affects dogs. Lymphoma is a type of cancer that affects the lymphatic system.
- Osteosarcoma. Osteosarcoma is the most common type of bone cancer that occurs in dogs. It begins as a tumor that often affects the long bones of the limbs, but it can affect any bones in the body.
- Hemangiosarcoma. Hemangiosarcoma is often considered the most aggressive dog cancer. It affects the lining of blood vessels in the body and commonly occurs in the spleen, heart, or liver.
- Breast Cancer. Breast cancer is relatively common in dogs. Most mammary tumors tumors are carcinomas that begin as a lump on the abdomen near the dog's nipples.
- What Are Neuroendocrine Tumors?
- What Causes These Tumors?
- What Are The Signs of These Tumors?
- How Are These Tumors Diagnosed?
- How Do These Tumors Typically Progress?
- What Are The Treatments For These Tumors?
- Is There Anything Else I Should Know?
Neuroendocrine tumors are a group of tumors that develop from the disorganized uncontrolled proliferation of the cells of the neuroendocrine system. The neuroendocrine system is made up of special cells called neuroendocrine cells. Neuroendocrine cells are like nerve cells (neurons), but they also make hormones like cells of the endocrine system (e...
The reason why a particular pet may develop this, or any tumor or cancer, is not straightforward. Very few tumors and cancers have a single known cause. Most seem to be caused by a complex mix of risk factors, some environmental and some genetic or hereditary. Chemodectomas are seen most often in brachycephalic (flat-faced) dogs such as Boxers and ...
The signs of these tumors depend on the type of, location, and size of the tumor, as well as the degree of infiltration into the surrounding tissues, and whether the tumor has spread to other areas of the body. It also depends on whether the tumors are functional (i.e., whether they produce excessive hormone). The signs of insulinomas relate to the...
These tumors are diagnosed in a variety of ways, in relation to where they are located and how they affect the body. Some tumors are diagnosed in part with blood work. For example, with insulinomas blood work will show a low blood sugar along with a normal or high blood insulin. With gastrinomas, there will be higher than normal levels of gastrin i...
Most of these tumors have the tendency to spread to other areas of the body. The rate and extent of metastasis depends on the type of tumor. Common sites of metastasis include the lymph nodes, lungs, liver, kidneys, heart, bone, and brain. Staging(searching for potential spread to other locations in the body) is highly recommended for these tumors....
The choice of treatments for these tumors depends on the type, size, and malignancy of the tumor, as well as the presence of metastasis. Treatment typically involves several options, including surgery, chemotherapy, radiation therapy, and medical and dietary approaches. Your veterinarian may refer your pet to a veterinary oncologist to develop a pl...
As neuroendocrine tumors are rare, should these tumors be suspected or diagnosed, your veterinarian may refer you to a veterinary oncologist. Because many of the signs of these tumors are symptomatic of many common illnesses, and may wax and wane, these tumors can be difficult to diagnose. With treatment, the prognosis for your pet may range from g...
Merkel cell carcinoma (MCC) is in humans and cats a malignant cutaneous neuroendocrine carcinoma, whereas in dogs it possibly has a more benign behavior. It may be cytologically confused with round cell tumors such as lymphoma because of its striking cytomorphologic similarity.
Dec 6, 2022 · Merkel cell carcinoma is a rare type of skin cancer that usually appears as a flesh-colored or bluish-red nodule, often on your face, head or neck. Merkel cell carcinoma is also called neuroendocrine carcinoma of the skin. Merkel cell carcinoma most often develops in older people.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine tumor, and most human MCC cases are infected by Merkel cell polyomavirus (MCPyV). However, the underlying pathogeneses of MCC in animals remain unclear. In the present study, newly established cell lines from feline and canine MCC, a MCPyV-positive human MCC cell line, and ...
