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  1. During development, tissues are replaced by bone during the ossification process. In intramembranous ossification, bone develops directly from sheets of mesenchymal connective tissue. In endochondral ossification, bone develops by replacing hyaline cartilage.

    • Lindsay M. Biga, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Mat...
    • 2019
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  3. Apr 9, 2024 · Bone ossification is the formation of new bone, which can occur in two ways: intramembranous ossification and endochondral ossification. This article will discuss both forms as well as clinically relevant examples.

  4. May 1, 2023 · Endochondral Ossification. This process involves the replacement of hyaline cartilage with bone. It begins when mesoderm-derived mesenchymal cells differentiate into chondrocytes. Chondrocytes proliferate rapidly and secrete an extracellular matrix to form the cartilage model for bone.

    • Grant Breeland, Margaret A. Sinkler, Ritesh G. Menezes
    • 2023/05/01
    • 2019
  5. Oct 30, 2023 · Bone formation in a developing embryo begins in mesenchyme and occurs through one of two processes: either endochondral or intramembranous osteogenesis (ossification). Intramembranous ossification is characterized by the formation of bone tissue directly from mesenchyme. Flat bones, such as the parietal and occipital bones, are formed using ...

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  6. en.wikipedia.org › wiki › OssificationOssification - Wikipedia

    Ossification (also called osteogenesis or bone mineralization) in bone remodeling is the process of laying down new bone material by cells named osteoblasts. It is synonymous with bone tissue formation. [1]

  7. Jun 12, 2024 · All bone formation is a replacement process. Embryos develop a cartilaginous skeleton and various membranes. During development, these are replaced by bone during the ossification process. In intramembranous ossification, bone develops directly from sheets of mesenchymal connective tissue.

  8. Endochondral Ossification. In endochondral ossification, bone develops by replacing hyaline cartilage. Cartilage does not become bone. Instead, cartilage serves as a template to be completely replaced by new bone. Endochondral ossification takes much longer than intramembranous ossification.

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