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  1. Sepsis or Septic Shock Clinical Pathway in the Hematology/Oncology/BMT Clinical Pathway. Nursing: Complete Q4 hour Sepsis Screening Assessment OR if concern for sepsis or deteriorating condition, may complete assessment at any time. Providers: Assess within 15 minutes of notification and select Huddle Outcome.

  2. May 9, 2023 · The recognition of sepsis in children is challenging and is related to the high prevalence of common febrile infections, poor specificity of discriminating features, and some capacity of children’s physiology to compensate until shock is in an advanced stage [1••]. Sepsis outcomes in children are strongly dependent on the timeliness of ...

  3. Dec 12, 2023 · Sepsis and septic shock are major causes of morbidity, mortality, and health care costs for children worldwide, including >3 million deaths annually and, among survivors, risk for new or worsening functional impairments, including reduced quality of life, new respiratory, nutritional, or technological assistance, and recurrent severe infections. Advances in understanding sepsis pathophysiology ...

  4. Jul 3, 2020 · 1. INTRODUCTION AND EPIDEMIOLOGY. Sepsis contributes to 19% of all deaths globally, with the highest age‐specific incidence in children younger than 5 years of age. 1 , 2 Pediatric sepsis resulted in 0.7% of all hospital encounters, with an incidence of 2.8% in inpatients in the United States. 3 Epidemiologic studies using clinical data have found an incidence of pediatric sepsis in up to 8% ...

    • Andrea T. Cruz, Roni D. Lane, Fran Balamuth, Paul L. Aronson, David W. Ashby, Mark I. Neuman, Ellie ...
    • 10.1002/emp2.12173
    • 2020
    • 2020/10
  5. May 25, 2022 · Each year, an estimated 25 million neonates, children, and adolescents suffer from sepsis, leading to over 3 million deaths globally. 1 Yet, controversy surrounds the attempts to operationalize the definition of sepsis in pediatric age groups and poses a major obstacle to implementation of the World Health Organization (WHO) resolution designating sepsis as a global health priority. 2 Children ...

    • Morin, Luc
  6. May 22, 2024 · Sepsis is a clinical syndrome that complicates severe infection and is characterized by the systemic inflammatory response syndrome (SIRS), immune dysregulation, microcirculatory derangements, and end-organ dysfunction. In this syndrome, tissues remote from the original insult display the cardinal signs of inflammation, including vasodilation ...

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  8. Apr 16, 2020 · Global Burden of Sepsis in ChildrenSepsis affects more than 25 million children every year, representing over half of all sepsis case worldwide.2 • More than 80% of all pediatric sepsis cases and 40% of all sepsis cases occur in children under age 5 years (20.3 million cases).2 • Globally, sepsis is the leading cause of death of ...

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