Search results
Jul 4, 2023 · Hereditary spherocytosis results from a deficiency in one or more proteins involved in maintaining adequate adherence between the cytoskeleton and bilipid membrane. As the cellular surface is unable to be adequately supported by the cytoskeleton, the cell adopts an abnormal sphere shape that decreases surface to volume relationship.
- Edgar A. Zamora, Catherine A. Schaefer
- 2023/07/04
Oct 24, 2021 · The HS diagnostic protocol developed by Shen et al. 7 describes spherocytes and/or microspherocytes as a diagnostic indicator in more detail. Microspherocytes that are deeply stained with small cell bodies and disappearance of central lightly stained region are shown in the blood smear tests.
- Yangyang Wu, Lin Liao, Faquan Lin
- J Clin Lab Anal. 2021 Dec; 35(12): e24034.
- 10.1002/jcla.24034
- 2021/12
3 days ago · Hereditary spherocytosis is an inherited abnormality of the red blood cell, caused by defects in structural membrane proteins. It is the most common form of inherited haemolytic anaemia in the US and northern Europe.
Abstract. Newborn infants who have hereditary spherocytosis (HS) can develop anemia and hyperbilirubinemia. Bilirubin-induced neurologic dysfunction is less likely in these neonates if the diagnosis of HS is recognized and appropriate treatment provided.
- Robert D. Christensen, Hassan M. Yaish, Patrick G. Gallagher
- 10.1542/peds.2014-3516
- 2015
- Pediatrics. 2015 Jun; 135(6): 1107-1114.
Hereditary spherocytosis and hereditary elliptocytosis are congenital red blood cell (RBC) membrane disorders that can cause a mild hemolytic anemia. Symptoms, generally milder in hereditary elliptocytosis, include variable degrees of anemia, jaundice, and splenomegaly.
Hereditary spherocytosis is a rare inherited disorder that requires lifelong medical care. Healthcare providers can treat the sometimes-serious medical conditions that hereditary spherocytosis causes. They can’t cure the blood disorder, though. It’s not always easy to have a chronic illness or care for someone who does.
People also ask
Is spherocytosis hereditary?
How is hereditary spherocytosis treated?
What does spherocytosis mean?
What is the differential diagnosis for hereditary spherocytosis?
Mar 15, 2023 · Consumer information about hereditary spherocytosis, a condition in which a person's red blood cells are spherical rather than the normal concave disk shape of red blood cells. Symptoms of hereditary spherocytosis include jaundice (yellowing of the skin and whites of the eyes), enlarged spleen, gallbladder problems, and anemia.
