Search results
Hereditary spherocytosis is a rare inherited disorder that requires lifelong medical care. Healthcare providers can treat the sometimes-serious medical conditions that hereditary spherocytosis causes.
3 days ago · Hereditary spherocytosis is an inherited abnormality of the red blood cell, caused by defects in structural membrane proteins. It is the most common form of inherited haemolytic anaemia in the US and northern Europe.
Oct 24, 2021 · Hereditary spherocytosis (HS) is a hereditary hemolytic anemia caused by the mutations in the genes encoding erythrocyte membrane proteins and is mostly inherited in an autosomal dominant manner. 1, 2, 3 HS is classified into four types according to the severity of the disease: trait, mild, moderate, and severe. Commonly, there is heterogeneity ...
- Yangyang Wu, Lin Liao, Faquan Lin
- J Clin Lab Anal. 2021 Dec; 35(12): e24034.
- 10.1002/jcla.24034
- 2021/12
Newborn infants who have hereditary spherocytosis (HS) can develop anemia and hyperbilirubinemia. Bilirubin-induced neurologic dysfunction is less likely in these neonates if the diagnosis of HS is recognized and appropriate treatment provided.
- Robert D. Christensen, Hassan M. Yaish, Patrick G. Gallagher
- 10.1542/peds.2014-3516
- 2015
- Pediatrics. 2015 Jun; 135(6): 1107-1114.
Hereditary spherocytosis and hereditary elliptocytosis are congenital red blood cell (RBC) membrane disorders that can cause a mild hemolytic anemia. Symptoms, generally milder in hereditary elliptocytosis, include variable degrees of anemia, jaundice, and splenomegaly.
Hereditary spherocytosis occurs in 1 in 2,000 individuals of Northern European ancestry. This condition is the most common cause of inherited anemia in that population. The prevalence of hereditary spherocytosis in people of other ethnic backgrounds is unknown, but it is much less common.
People also ask
What is hereditary spherocytosis?
How is hereditary spherocytosis treated?
What does spherocytosis mean?
How many people have hereditary spherocytosis?
Mar 15, 2023 · Spherocytosis is the production of red blood cells (erythrocytes) that are in the shape of a sphere (spherocytes) instead of the concave disk shape that is normal for red blood cells. These spherocytes are abnormal, fragile, and possess a short lifespan as compared to normal red blood cells.
