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  1. Jan 17, 2019 · The typical clinical picture of HS combines signs and symptoms of hemolysis (anemia, jaundice, reticulocytosis, gallstones, splenomegaly) with spherocytosis (spherocytes on the peripheral blood...

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    • What Is Hereditary spherocytosis?
    • Who Is Affected by Hereditary spherocytosis?
    • How Does Hereditary Spherocytosis Affect My body?

    Hereditary spherocytosis is an inherited blood disorder that causes hemolytic anemia. This anemia happens when your red blood cellsbreak down faster than normal. In hereditary spherocytosis, your red blood cells lose their characteristic disk-like shape, becoming round or spherical cells (spherocytes) that are removed from circulation faster than n...

    Hereditary spherocytosis typically affects people who have Northern Europe or North American ancestry. (Northern Europe is the northern part or region of the European continent.) Data vary on how many people have hereditary spherocytosis. Healthcare providers estimate that 1 person in 2,000 to 5,000 people worldwide may have hereditary spherocytosi...

    In addition to developing hemolytic anemia, most people who have hereditary spherocytosis may have the following conditions: 1. Enlarged spleen (splenomegaly): People develop enlarged spleens in hereditary spherocytosis when their spleens fill up with spherocytes. Blood cells flow through your spleen, navigating several narrow passages before movin...

  3. Feb 14, 2024 · Hereditary spherocytosis is a disorder in which the red blood cells are abnormal and fragile. Learn about the causes, symptoms, and treatment options for this disorder today.

  4. Mar 6, 2023 · In most people, splenectomy — or removal of the spleen — can cure symptoms. However, this procedure can increase the risk of serious infections and pose other surgery-related risks.

  5. Jul 4, 2023 · Summarize the treatment of hereditary spherocytosis. Identify the importance of improving care coordination among the interprofessional team in the prompt recognition of hereditary spherocytosis and referring these patients to a hematologist for better management.

    • Edgar A. Zamora, Catherine A. Schaefer
    • 2023/07/04
  6. Oct 24, 2021 · Hereditary spherocytosis (HS), a commonly encountered hereditary hemolytic disease, is mostly inherited in an autosomal‐dominant manner. The clinical manifestations in patients with HS show obvious heterogeneity.

  7. 2 days ago · In these cases, hereditary spherocytosis (HS) may be detected on a blood count/smear done for other reasons. Management depends on the severity of the haemolysis and degree of anaemia, but is generally supportive for most patients. Splenectomy is the treatment of choice in patients with severe HS.

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