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  1. Jul 4, 2023 · Summarize the treatment of hereditary spherocytosis. Identify the importance of improving care coordination among the interprofessional team in the prompt recognition of hereditary spherocytosis and referring these patients to a hematologist for better management.

    • Edgar A. Zamora, Catherine A. Schaefer
    • 2023/07/04
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  3. Oct 24, 2021 · Through combing our research with existing experimental technologies and studies, we propose a simple and practical protocol for HS diagnosis, which will help clinicians to improve HS diagnosis.

    • Yangyang Wu, Lin Liao, Faquan Lin
    • J Clin Lab Anal. 2021 Dec; 35(12): e24034.
    • 10.1002/jcla.24034
    • 2021/12
  4. The most effective therapy is splenectomy. In symptomatic patients, partial or total splenectomy is recommended. 2 Basics. 2.1 Definition and basic information. Hereditary spherocytosis (HS) is a heterogeneous group of disorders of erythrocytes.

  5. Mar 18, 2021 · Gene therapy aims to provide a functional gene copy of the damaged gene (s), increase the availability of disease-modifying genes or suppress the activity of a damaged gene. 6, 7 Gene therapy has a broad spectrum of applications, from gene replacement and knockdown for genetic disorders including cancer, hemophilia, hypercholesterolemia, and neu...

    • Tafere Mulaw Belete
    • 10.2147/BTT.S302095
    • 2021
    • Biologics. 2021; 15: 67-77.
  6. Jan 17, 2019 · Hereditary spherocytosis (HS) refers to a group of disorders characterized by spherical, doughnut-shaped erythrocytes with increased osmotic fragility. The clinical manifestations of the...

  7. 2 days ago · In these cases, hereditary spherocytosis (HS) may be detected on a blood count/smear done for other reasons. Management depends on the severity of the haemolysis and degree of anaemia, but is generally supportive for most patients. Splenectomy is the treatment of choice in patients with severe HS.

  8. Feb 16, 2022 · Spherocytosis is not curable, but medical attention can help improve the outcome and quality of life and prevent complications. Treatments include: Folate : Sometimes, folate supplementation can help improve red blood cell formation.

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