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1. • • Spherocytosis is not curable, but medical attention can help improve the outcome and quality of life and prevent complications.
     www.verywellhealth.com › spherocytosis-5217815

     Spherocytosis: Overview and More - Verywell Health

2. www.ncbi.nlm.nih.gov › books › NBK539797Hereditary Spherocytosis - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK539797

   Jul 4, 2023 · Summarize the treatment of hereditary spherocytosis. Identify the importance of improving care coordination among the interprofessional team in the prompt recognition of hereditary spherocytosis and referring these patients to a hematologist for better management.

   • Author: Edgar A. Zamora, Catherine A. Schaefer

   • Published: 2023/07/04

3. People also ask

   How is hereditary spherocytosis treated?

   • There is no causal therapy. In many patients, an observational approach is indicated. The most effective therapy is splenectomy. In symptomatic patients, partial or total splenectomy is recommended. Hereditary spherocytosis (HS) is a heterogeneous group of disorders of erythrocytes.

   Hereditary Spherocytosis (Spherocytic Anemia) - Onkopedia

   www.onkopedia-guidelines.info/en/onkopedia/guidelines/hereditary-spherocytosis-spherocytic-anemia

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   Is spherocytosis inherited?

   • Hereditary spherocytosis (HS) is an inherited disorder characterized by anemia, splenomegaly, and spherical-shaped erythrocytes, caused by mutations in erythrocyte membrane Protein Genes ( ANK1, SPTB, SLC4A1, SPTA1, and EPB42 ). We investigated molecular spectrum and genotype-phenotype correlation in HS patients in Hubei province, central China.

   Genetic and Clinical Characteristics of Patients With Hereditary

   www.ncbi.nlm.nih.gov/pmc/articles/PMC7461774/

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   Does spherocytosis increase the risk of infection after a splenectomy?

   • Patients with hereditary spherocytosis who require splenectomy later in life have a high risk of hospital admission for infections, especially those with severe hereditary spherocytosis. With vaccines or postoperative antibiotics, splenectomy does not increase the risk of infection or severe infections.

   Hereditary spherocytosis before and after splenectomy and risk of

   www.nature.com/articles/s41390-022-02229-y

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   What is the differential diagnosis for hereditary spherocytosis?

   • The differential diagnosis for patients with hereditary spherocytosis is broad and includes other red blood cell disorders including elliptocytosis and its variants, hereditary stomatocytosis, pyropoikilocytosis, and ovalocytosis.

   Hereditary Spherocytosis - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov/books/NBK539797/

   See all results for this question

4. www.ncbi.nlm.nih.gov › pmc › articlesThe diagnostic protocol for hereditary spherocytosis‐2021 ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Oct 24, 2021 · Through combing our research with existing experimental technologies and studies, we propose a simple and practical protocol for HS diagnosis, which will help clinicians to improve HS diagnosis.

   • Author: Yangyang Wu, Lin Liao, Faquan Lin
   • Publication: J Clin Lab Anal. 2021 Dec; 35(12): e24034.

   • DOI: 10.1002/jcla.24034
   • Published: 2021/12

5. onlinelibrary.wiley.com › doi › pdfBritish Journal of Haematology | Wiley Online Library

   onlinelibrary.wiley.com › doi › pdf

   Nov 5, 2011 · Guidelines on hereditary spherocytosis (HS) published in 2004 (Bolton-Maggs et al, 2004) are here replaced to reflect changes in current opinion on the surgical management, (particularly the indications for concomitant splenectomy with cholecystectomy in children with mild HS, and concomitant cholecystectomy with splenectomy in those with asympt...

   • Author: Paula H. B. Bolton-Maggs, Jacob C. Langer, Achille Iolascon, Paul Tittensor, May-Jean King

   • Publish Year: 2012

6. www.ncbi.nlm.nih.gov › pmc › articlesGenetic and Clinical Characteristics of Patients With ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Aug 18, 2020 · Hereditary spherocytosis (HS) is an inherited disorder characterized by anemia, splenomegaly, and spherical-shaped erythrocytes, caused by mutations in erythrocyte membrane Protein Genes ( ANK1, SPTB, SLC4A1, SPTA1, and EPB42 ). We investigated molecular spectrum and genotype-phenotype correlation in HS patients in Hubei province, central China.

   • Author: Xiong Wang, Ai Zhang, Ming Huang, Li Chen, Qun Hu, Yanjun Lu, Liming Cheng
   • DOI: 10.3389/fgene.2020.00953

   • Publish Year: 2020
   • Publication: Front Genet. 2020; 11: 953.

7. www.onkopedia-guidelines.info › en › onkopediaHereditary Spherocytosis (Spherocytic Anemia) — Onkopedia

   www.onkopedia-guidelines.info › en › onkopedia

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   The most effective therapy is splenectomy. In symptomatic patients, partial or total splenectomy is recommended. 2 Basics. 2.1 Definition and basic information. Hereditary spherocytosis (HS) is a heterogeneous group of disorders of erythrocytes.

8. pubmed.ncbi.nlm.nih.gov › 28463670Hereditary Spherocytosis - Diagnosis, Surgical Treatment and ...

   pubmed.ncbi.nlm.nih.gov › 28463670

   Splenectomy is considered the standard surgical treatment in moderate and severe forms of hereditary spherocytosis. Total splenectomy exposes the patient to a life - long risk of potentially lethal infections and thus, its usage was reconsidered.

9. www.nature.com › articles › s41390/022/02229-yHereditary spherocytosis before and after splenectomy and ...

   www.nature.com › articles › s41390/022/02229-y

   Aug 1, 2022 · Impact Patients with hereditary spherocytosis who require splenectomy later in life have a high risk of hospital admission for infections, especially those with severe hereditary spherocytosis.