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Feb 16, 2022 · Treatment. Spherocytosis is a condition that causes a person’s red blood cells to be shaped like spheres (round balls) instead of their normal disk shape. It can cause symptoms of anemia (lack of healthy red blood cells) and an enlarged spleen (an organ that filters and stores blood). This condition is usually inherited.
Introduction. Immune-mediated hemolytic anemia (IMHA) is one of the most common and serious hemolytic anemias in dogs, but occurs rarely in other animal species. In IMHA an immune response, including anti-erythrocytic antibodies, complement and macrophages, targets directly or indirectly erythrocytes and a hemolytic anemia ensues.
Aug 5, 2021 · Abstract. Despite all good intentions, dogs are still running behind humans in effective cancer immunotherapies. The more effective treatments in humans, like infusions of CAR-T and NK-cells are not broadly pursued for canines due to significant costs, the rather complicated logistics and the lack of targetable surface antigens.
- Hans Klingemann
- 2021
Jul 14, 2019 · Lymphoma, a common cancer in dogs accounting for 8% of cancers is particularly susceptible to chemotherapy. The dog will not be cured by chemotherapy but may have its life prolonged from 2–24 months [ 12, 13 ]. The dog may feel better, still suffering from the cancer, or it may suffer from the side effects of the treatment.
- Tanya Stephens
- 2019
Feb 5, 2018 · The purpose of this brief review is to summarize the current status of available immunotherapies for dogs and their near-term prospects, provided we can effectively translate discoveries and progress in humans to canines. Keywords: comparative oncology, immunotherapy of cancer, canine, veterinary medicine, cancer immunotherapy. Go to:
- Hans Klingemann
- 2018
Dec 1, 2008 · Limited but favorable reports exist on the use of this drug for treating IMHA. Side effects in dogs appear to be minimal but can include vomiting, lymphopenia, and anemia. The recent introduction of a generic form may make it less costly for routine treatment. The dose should be adjusted to maintain a serum trough concentration of 20 µg/ml.31 ...
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What is spherocytosis & how is it treated?
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Why is spherocytosis dangerous?
Oct 25, 2023 · INTRODUCTION. Although relatively rare, hereditary spherocytosis (HS) is the most common cause of hemolytic anemia due to a red cell membrane defect. It is a result of heterogeneous alterations in one of five genes that encode red blood cell (RBC) membrane proteins involved in vertical associations that link the membrane cytoskeleton to the ...
