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  1. Aug 1, 2021 · This guideline addresses the evaluation and management of well-appearing, term infants, 8 to 60 days of age, with fever ≥38.0°C. Exclusions are noted.

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  3. May 1, 2012 · The purpose of this clinical report is to provide a practical and, when possible, evidence-based approach to the diagnosis and management of early-onset sepsis, defined by the National Institute of Child Health and Human Development and Vermont Oxford Networks as sepsis with onset at ≤3 days of age.

    • Richard A. Polin, Newborn
    • 2012
  4. Dec 1, 2018 · Our purpose in this clinical report is to provide a summary of the current epidemiology of neonatal sepsis among infants born at ≥35 0/7 weeks’ gestation and a framework for the development of evidence-based approaches to sepsis risk assessment among these infants.

    • Karen M. Puopolo, Karen M. Puopolo, William E. Benitz, Theoklis E. Zaoutis, Newborn
    • 2018
  5. Management of Neonates Born at Less Than or Equal to 35 0/7 Weeks' Gestation With Suspected or Proven Early-Onset Bacterial Sepsis. Pediatrics 142: e20182894. Verani JR, et al. 2010.

  6. Sep 29, 2022 · Objectives: Assess the etiology of early and late-onset neonatal sepsis. Evaluate various clinical and laboratory findings associated with neonatal sepsis. Differentiate the various treatment and management options available for neonatal sepsis.

    • Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray
    • 2022/09/29
  7. NICE guidelines versus AAP Committee on Fetus and Newborn guidelines. The UK 11 and the USA 12 have published guidelines for managing infants with suspected and proven early onset sepsis. The UK (NICE) guidelines were updated in April 2021 and the US AAP guidelines were published in December 2018.

  8. Jul 1, 2022 · Fluid administration plays a major role in the initial management of septic shock. If there is no response to volume filling, inotropes must be infused within one hour of onset (dopamine, dobutamine, adrenaline). Life-threatening infections require immediate and aggressive empiric use of antimicrobials.

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