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  1. Aug 1, 2021 · This guideline addresses the evaluation and management of well-appearing, term infants, 8 to 60 days of age, with fever ≥38.0°C. Exclusions are noted.

  2. Early diagnosis of neonatal sepsis is important and requires awareness of risk factors (particularly in LBW neonates) and a high index of suspicion when any neonate deviates from the norm in the first few weeks of life.

  3. The diagnosis and management of neonatal sepsis is one of the commonest challenges faced by Pediatricians in day-to-day clinical practice. Conventionally, neonatal sepsis is classified according to the time of onset as EONS (onset at <72 hours of life) and LONS

  4. Goals. Provide guidance on the assessment and management of newborns in the NICU and NBN who are at increased risk of early onset bacterial infection with onset in the first 72 hours of life. le assuring that newborns who require antimicrobial treatment are treate.

  5. Mar 29, 2015 · The American Academy of Pediatrics (AAP) Committee on Fetus and Newborn 7 has published a clinical report extensively discussing clinically relevant challenges: identifying newborns with signs of sepsis with high likelihood of EOS requiring antimicrobial regimen and identifying healthy-appearing newborns with high likelihood of EOS requiring ant...

    • Roberto Parulan Santos, Debra Tristram
    • 10.1016/j.pcl.2014.11.010
    • 2015
    • 2015/04
  6. May 1, 2012 · Neonatal sepsis is a major cause of morbidity and mortality. Diagnostic tests for early-onset sepsis (other than blood or CSF cultures) are useful for identifying infants with a low probability of sepsis but not at identifying infants likely to be infected.

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  8. NICE guidelines versus AAP Committee on Fetus and Newborn guidelines The UK11 and the USA12 have published guidelines for managing infants with suspected and proven early onset sepsis. The UK (NICE) guidelines were updated in April 2021 and the US AAP guidelines were published in December 2018.

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