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  1. The SEER database tracks 5-year relative survival rates for osteosarcoma in the United States, based on how far the cancer has spread. The SEER database, however, does not group cancers by MSTS or TNM stages (stage 1, stage 2, stage 3, etc.).

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  3. Is osteosarcoma fatal? Survival rates are almost 70% for patients whose osteosarcoma hasn’t metastasized. If the osteosarcoma has spread to more than one part of the body, the survival rate drops to 30% to 50%. Can osteosarcoma return after treatment? Yes, recurrence can happen sometimes, typically within 18 months following treatment.

  4. May 23, 2023 · Last Update: May 23, 2023. Go to: Continuing Education Activity. Osteosarcoma is a malignant osseous neoplasm. It is the most common primary bone cancer of childhood. Less frequently, it occurs in adults where it represents secondary malignant degeneration of primary bone pathology.

    • Stephanie Prater, Brett McKeon
    • 2023/05/23
    • Aventura Hospital & Medical Center
  5. Apr 9, 2018 · For most of the twentieth century, five-year survival rates for classic OS were 20%. In the 1970s, the introduction of adjuvant chemotherapy in the treatment of OS increased survival rates to 50% [ 2 – 4 ]. Before the mid-1970s, amputation was the routine treatment for high-grade OS.

    • Amirhossein Misaghi, Amanda Goldin, Moayd Awad, Anna A Kulidjian
    • 2018
  6. For all registered patients at a median follow-up of 54 months (interquartile range: 38–73) from biopsy, 3-year and 5-year event-free survival were 59% (95% confidence interval [CI]: 57–61%) and 54% (95% CI: 52–56%), respectively.

    • Sigbjørn Smeland, Stefan S. Bielack, Jeremy Whelan, Mark Bernstein, Pancras Hogendoorn, Mark D. Krai...
    • 10.1016/j.ejca.2018.11.027
    • 2019
    • Eur J Cancer. 2019 Mar; 109: 36-50.
  7. Nov 24, 2021 · Approximately 10 to 15% of patients with newly diagnosed osteosarcoma present with metastatic disease, primarily in the lung. 3,4 The 5-year survival rate is approximately 60% among patients...

  8. Feb 28, 2022 · The overall 5-year RS rate was 65.9%; 95% CI, 63.7%-68.1% (Table 2 ). By decade, RS was 65.9% in the most recent decade, a statistically significant increase ( P < .05) as compared to the 1970s ( P < .001) and the 1980s ( P = .013); however, survival has decreased slightly since the 1990s and 2000s (Fig. 3B ).

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