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  1. May 23, 2022 · Muscle aches or pains. High blood pressure. Altered sense of taste. Diarrhea, nausea, and other gastrointestinal distress. Resistance to HIV medicines. All of...

    • zee.krstic@hearst.com
    • 2 min
    • Content Strategy Manager, Hearst Magazines
    • Taste changes (dysgeusia) An altered or bad taste in the mouth is the most commonly reported side effect with Paxlovid. People report a bitter or metallic taste (often referred to as “Paxlovid mouth”) that’s hard to get rid of while on treatment.
    • Diarrhea. Diarrhea is another side effect you may encounter during treatment with Paxlovid, but it’s also a side effect of COVID-19. For most people, diarrhea due to Paxlovid clears up after treatment and tends to be mild.
    • Blood pressure increase (hypertension) High blood pressure was listed as a side effect with Paxlovid, but it’s not very common. High blood pressure, also called hypertension, occurred in about 1% of people (1 out of everyone 100) in Paxlovid studies (and less than 1% in the placebo group).
    • Muscle aches and pain (myalgia) Muscle aches (myalgia) occurred in about 1% of people in studies with Paxlovid, and less than 1% of the placebo group.
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    • kathy.katella-cofrancesco@yale.edu
    • How does Paxlovid work? Paxlovid is an antiviral therapy that consists of two separate medications packaged together. When you take your three-pill dose, two of those pills will be nirmatrelvir, which inhibits a key enzyme that the COVID virus requires in order to make functional virus particles.
    • When should I take Paxlovid? You have to take Paxlovid within five days of developing symptoms. Like all antivirals, Paxlovid works best early in the course of an illness—in this case, within the first five days of symptom onset, says Jeffrey Topal, MD, a Yale Medicine infectious diseases specialist who is involved in determining COVID-19 treatment protocols for Yale New Haven Hospital patients.
    • How often do I take Paxlovid? The standard dose is three Paxlovid pills twice daily for five days for a full course that adds up to 30 pills. It helps that the pills are packaged in a “dose card,” basically a medication blister pack that allows you to punch out the pills as needed.
    • Is Paxlovid similar to Tamiflu? “I think it's a good comparison,” says Dr. Roberts. Tamiflu is an antiviral drug that reduces flu symptoms. Both are prescription-only oral antiviral pills given early in illness.
  2. May 23, 2022 · Other side effects seen in the trial, and these are quite common with this protease inhibitor class, there are metallic taste on the tongue, as well as diarrhea and loose stools. And you should warn your patients about that.

  3. PAXLOVID may cause side effects, some of which may be serious, such as allergic reactions or liver problems. The list below doesn't include all of the possible side effects of PAXLOVID. For more information, ask your healthcare professional or pharmacist. Some side effects of PAXLOVID are:

  4. 1 . Revised: 03/2024. What is the most important information I should know about PAXLOVID? PAXLOVID can interact with other medicines causing severe or life-threatening side effects or death....

  5. Common side effects. These common side effects of Paxlovid happen in up to 1 in 10 people. There are things you can do to help cope with them: Diarrhoea. Feeling sick or being sick (nausea or vomiting) Changes in your sense of taste.

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  2. Talk to your doctor to see if SKYCLARYS is an option for you. Patients, learn more about clinical trial results. See product & safety information here.

  3. Find Important Safety Information And Review Possible Side Effects Of A Medication Option. Get Helpful HIV Medication Patient Resources Here & Talk With Your Doctor About Treatment.

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