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  1. Dec 17, 2022 · Minipress (prazosin), a drug commonly used to treat high blood pressure and urinary retention, has been shown in some studies to be safe and effective in managing nightmares and sleep disturbances in people with post-traumatic stress disorder (PTSD).

  2. Oct 18, 2023 · Prazosin — Prazosin, an alpha-1 adrenergic receptor antagonist, is the best studied medication for nightmares and has been the preferred first-line pharmacotherapy when medication is deemed necessary .

  3. Sep 7, 2022 · One possible medical treatment for post-traumatic stress disorder (PTSD) nightmares is the drug prazosin. It can relax the muscles and reduce blood pressure and may decrease the number of...

  4. Prazosin is a well-tolerated generically available medication that has a small but positive evidence base for the treatment of PTSD-associated nightmares. Given the difficulty of treating nightmares, combined with the continued presence of patients with nightmares, prazosin can be an important pharmacologic treatment option.

  5. Aug 17, 2023 · Prazosin has therapeutic use for benign prostatic hypertrophy (BPH), post-traumatic stress disorder (PTSD) associated nightmares, Raynaud phenomenon, pheochromocytoma, and scorpion envenomation. Prazosin was the first alpha antagonist used for BPH.

  6. Nightmares, frequently associated with posttraumatic stress disorder and clinically relevant in today’s world of vio-lence, are difficult to treat, with few pharmacologic options. We performed a systematic review to evaluate the evidence for the use of prazosin in the treatment of nightmares.

  7. Mar 5, 2012 · ROCHESTER, Minn. — Mayo Clinic researchers this week will announce the use of the blood pressure drug prazosin as an effective treatment to curb post-traumatic stress disorder (PTSD)-related nightmares.

  8. Oct 8, 2010 · Prazosin demonstrated favorable clinical efficacy and was found to be safe for relieving PTSD-associated nightmares. Conclusions: Current data indicate that prazosin is an effective agent for the treatment of nightmares associated with PTSD.

  9. Adults—At first, 1 milligram (mg) 2 or 3 times a day. Your doctor will slowly increase your dose as needed. However, the dose is usually not more than 20 mg per day. Children—Use and dose must be determined by your doctor. Missed Dose. If you miss a dose of this medicine, take it as soon as possible.

  10. Aug 15, 2010 · Treatment modalities for nightmare disorder include medications, most prominently prazosin, and several behavioral therapies, of which the nightmare-focused cognitive behavioral therapy variants, especially image rehearsal therapy, are effective.

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