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Antithyroid agents
- Drug class: Antithyroid agents
Jun 5, 2023 · Propylthiouracil is an anti-thyroid drug used to manage Graves disease and hyperthyroidism. This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., dosing, pharmacodynamics, pharmacokinetics, monitoring, relevant interactions) of propylthiouracil pertinent for healthcare team members in the ...
- Fnu Amisha, Anis Rehman
- 2023/06/05
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- What Is Propylthiouracil?
- Propylthiouracil Side Effects
- Warnings
- Before Taking This Medicine
- How Should I Take Propylthiouracil?
- What Happens If I Miss A dose?
- What Happens If I Overdose?
- What Should I Avoid While Taking Propylthiouracil?
- What Other Drugs Will Affect Propylthiouracil?
- Further Information
Propylthiouracil is used to treat hyperthyroidism (overactive thyroid), Graves' disease, or toxic goiter (enlarged thyroid). propylthiouracil is sometimes given to control symptoms just before you undergo thyroid surgery or treatment with radioactive iodine. Propylthiouracil may also be used for purposes not listed in this medication guide.
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling). Propylthiouracil can cause liver damage (especially during the first 6 months of treatment). ...
Propylthiouracil can cause serious or fatal liver problems. Stop taking propylthiouracil and call your doctor right away if you haveupper stomach pain, nausea, vomiting, loss of appetite, fever, itching, tiredness, dark urine, clay-colored stools, or yellowing of your skin or eyes.
You should not use propylthiouracil if you are allergic to it. Tell your doctor if you have ever had liver problems. In very rare cases, propylthiouracil has caused liver failure and death in pregnant women during the second or third trimester of pregnancy. Tell your doctor if you are pregnant or plan to become pregnant. Tell your doctor if you are...
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed. Propylthiouracil is usually taken 3 times per day. You will need frequent blood tests to check your thyroid. Call your doctor if you have unusual bruising or blee...
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time. Get your prescription refilled before you run out of medicine completely.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include fever, chills, itching, upset stomach, nausea, vomiting, swelling, headache, or joint pain.
Avoid driving or hazardous activity until you know how propylthiouracil will affect you. Your reactions could be impaired.
Tell your doctor about all your other medicines, especially: 1. digoxin (digitalis); 2. theophylline; 3. heart or blood pressure medication; or 4. a blood thinner--warfarin, Coumadin, Jantoven. This list is not complete. Other drugs may affect propylthiouracil, including prescription and over-the-counter medicines, vitamins, and herbal products. No...
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Medical Disclaimer Copyright 1996-2024 Cerner M...
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Jun 10, 2024 · The thionamides, methimazole, carbimazole, and propylthiouracil (PTU), are effective treatment of patients with Graves' hyperthyroidism. They are actively transported into the thyroid gland where they inhibit both the organification of iodine to tyrosine residues in thyroglobulin and the coupling of iodotyrosines ( figure 1 ) [ 1 ].
Jul 7, 2021 · The aim of this study was to evaluate the efficiency and safety of methimazole (MMI) and propylthiouracil (PTU) in the treatment of hyperthyroidism. Methods: Articles were searched through the PubMed, EMBASE, Cochrane Library, Web of Science, CNKI, Wanfang, and QVIP.
- Shuang Tan, Long Chen, Likun Jin, Xiaomin Fu
- 10.1097/MD.0000000000026707
- 2021
- 2021/07/07
Propylthiouracil is classified as Drug Class D in pregnancy. Class D signifies there is positive evidence of human fetal risk. The maternal benefit may outweigh fetal risk in life-threatening situations.
Class. antithyroid agents. Pharm. Class. thioamides. Indications. Graves' disease with hyperthyroidism or toxic multinodular goiter in patients who are intolerant to methimazole and for whom surgery or radioactive iodine therapy is not appropriate.
Oct 9, 2023 · Propylthiouracil (PTU) is an oral medicine used: in patients with Graves’ disease with hyperthyroidism (overactive thyroid) or toxic goiter (enlarged thyroid) who are intolerant of methimazole and for whom surgery or radioactive iodine therapy is not an appropriate treatment option.
