Search results
4 days ago · Clozapine, which has a high affinity for serotonin receptors, has been shown to be more effective in treatment-resistant schizophrenia. Then, there is increased interest in the role of serotonin in pathogenesis and treatment of schizophrenia.
People also ask
Does serotonin affect neurotransmitters in schizophrenia?
Does schizophrenia have a serotonin system?
What is the serotonin hypothesis of schizophrenia?
Jan 1, 2020 · The concept of how the serotonin system is involved in the origin and progress of schizophrenia has changed considerably over the past decades. Therefore, this chapter gives an overview about the development and the current directions of the serotonin hypothesis of schizophrenia.
- Boris B. Quednow, Mark A. Geyer, Adam L. Halberstadt
- 2010
This chapter focuses on the evidence for the role of serotonin (5-hydroxytryptamine; 5-HT) in the etiology and pathophysiology of schizophrenia and, to a limited extent, the mechanism of action of antipsychotic drugs.
Apr 8, 2022 · The primary positive, negative, and cognitive symptoms of schizophrenia have been associated with many neurotransmitters, but the subcortical dopamine dysfunction remains to be the key factor in psychotic symptoms. Presynaptic dopamine dysfunction appears to mediate psychosis in schizophrenia.
- 10.7759/cureus.23959
- 2022/04
- Cureus. 2022 Apr; 14(4): e23959.
Oct 28, 2020 · Dysfunction of normal brain activity of serotonin is associated with schizophrenia. The role of serotonin 6 and 7 receptors in schizophrenia, interaction with neurotransmitters and the effect of drugs on those receptors in schizophrenia are the goal of this review.
- Etsay Weldekidan Tsegay, Desalegn Getnet Demise, Nigus Alemu Hailu, Zenawi Hagos Gufue
- 2020
May 19, 2014 · The revised dopamine hypothesis states that dopamine abnormalities in the mesolimbic and prefrontal brain regions exist in schizophrenia. However, recent research has indicated that glutamate, GABA, acetylcholine, and serotonin alterations are also involved in the pathology of schizophrenia.
Aug 1, 2024 · The main relationship between serotonin and schizophrenia is that changes in serotonin concentration can contribute to the onset of schizophrenia, and conversely, schizophrenia can gradually affect the serotonergic systems of the brain ( 6 ). Nowadays, there is no consensus on which one comes first.
