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Nov 5, 2021 · The most common clinical manifestation of lupus pulmonary vasculitis is diffuse alveolar hemorrhage (DAH) due to the access of red blood cells within the alveolar spaces as a result of the widespread damage of the pulmonary vessels with disruption of the alveolar-capillary basement membrane .
- Table 2
Lupus vasculitis (LV) is one of the secondary vasculitides...
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It is the least common renal lupus vascular lesion that...
- PMC Free Article
As most lupus nephritis patients in the study suffered both...
- Controlled Clinical Trial of IV Cyclophosphamide Versus IV Methylprednisolone in Severe Neurological Manifestations in Systemic Lupus Erythematosus
Background: Severe neurological involvement in systemic...
- A Case Report
Systemic lupus erythematosus (SLE) is a relatively rare...
- Vascular Disease in Systemic Lupus Erythematosus
2. Epidemiology. Systemic lupus erythematosus (SLE) is a...
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Mar 15, 2004 · Splinter hemorrhages are longitudinal thin lines, red or brown in color, that occur beneath the nail plate. They are visible when capillaries within the epidermal ridges leak .
- Skin Conditions
- Vasculitis and Systemic Diseases
- Infectious Diseases
- Drug Reactions
- Other Causes
Splinter hemorrhages are commonly seen in conditions such as nail psoriasis and lichen planus. Nail psoriasis is an autoimmune disorder that causes skin cells to collect on your nails. Lichen planus is an inflammatory skin condition that often results in an itchy rash. Up to 35% of people with lichen planus reported having splinter hemorrhages.
Splinter hemorrhages may be due to inflammation of your blood vessels (vasculitis). Several diseases such as antiphospholipid syndrome and lupuscan cause vasculitis.
Bacterial infections such as endocarditis may cause splinter hemorrhages. Endocarditis is an infection of your heart valves. Studies show that 15% to 33% of people with endocarditis have splinter hemorrhages. People with chronic kidney disease also report them. This may be due to hemodialysisor a kidney transplant.
Splinter hemorrhages are found in 60% to 70% of people taking kinase inhibitors such as sunitinib and sorafenib. Kinase inhibitors are cancer medications that stop cancer cells from growing. Splinter hemorrhages are also more common in people taking blood thinners such as aspirin, warfarin, apixaban or rivaroxaban.
There are various other causes of splinter hemorrhages. They can occur because of a rare benign (noncancerous) tumor of your nail called onychomatricoma. They can look similar to a type of skin cancer called subungual melanoma.
Jul 24, 2017 · Splinter hemorrhages are tiny blood spots that appear underneath the nail. They look like splinters and occur when tiny blood vessels (capillaries) along the nail bed are damaged and burst. The...
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Jan 9, 2023 · Red or brown stripes: Lupus may cause red or brown stripes to appear below the nail bed. Also known as splinter hemorrhages, these stripes occur due to damage to the blood vessels.
Aug 26, 2017 · Systemic lupus erythematosus (SLE): This autoimmune disorder causes joint pain, blood clotting, and changes to the circulation in the fingers. In rare instances, splinter hemorrhages can be the...
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Aug 27, 2017 · Patients with SLE frequently show abnormalities of the vasculature of the nail folds marked by periungual erythema, splinter hemorrhages, and nail fold infarcts.
