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   How is sepsis diagnosed?

   • The guidelines recommend the Sequential Organ Failure Assessment (original and quick versions) as an important tool for early diagnosis. Respiratory, gastrointestinal, genitourinary, and skin and soft tissue infections are the most common sources of sepsis. Pneumonia is the most common cause of sepsis.

   Sepsis: Diagnosis and Management | AAFP

   www.aafp.org/pubs/afp/issues/2020/0401/p409.html

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   How will the who guideline help patients with sepsis?

   • This WHO guideline will use the best evidence to help patients and the healthcare workers looking after them. 3 It will focus on making global recommendations for early recognition, initial resuscitation, and the early treatment of sepsis during which periods patients are most vulnerable.

   Guidelines on the Clinical Management of Sepsis

   www.who.int/news/item/30-01-2024-guidelines-on-the-clinical-management-of-sepsis

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   Who is at risk for sepsis?

   • Sepsis can affect anyone, but people with any kind of infection, especially bacteremia, are at a particularly high risk. Other people who are at a high risk include: People older than 65 years old, newborns and infants, and pregnant people. People with medical conditions such as diabetes, obesity, cancer and kidney disease.

   Sepsis: Symptoms, Causes, Treatment & Prevention - Cleveland Clinic

   my.clevelandclinic.org/health/diseases/12361-sepsis

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2. www.mayoclinic.org › diseases-conditions › sepsisSepsis - Symptoms & causes - Mayo Clinic

   www.mayoclinic.org › diseases-conditions › sepsis

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   Feb 10, 2023 · Sepsis is a serious condition in which the body responds improperly to an infection. The infection-fighting processes turn on the body, causing the organs to work poorly. Sepsis may progress to septic shock.

3. my.clevelandclinic.org › health › diseasesSepsis: Symptoms, Causes, Treatment & Prevention

   my.clevelandclinic.org › health › diseases

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   Jan 19, 2023 · You may have sepsis if you have confirmed or probable infection and at least two of the following criteria: Low blood pressure: Systolic blood pressure (the top number) reading of less than 100 mmHg (millimeters of mercury).

4. www.who.int › news-room › fact-sheetsSepsis - World Health Organization (WHO)

   www.who.int › news-room › fact-sheets

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   May 3, 2024 · Key facts. Sepsis is one of the most frequent causes of death worldwide, but there are challenges in collecting reliable data at the population level (1). From data published in 2020, there were 48.9 million cases and 11 million sepsis-related deaths worldwide, representing 20% of all global deaths (2).

5. www.ncbi.nlm.nih.gov › books › NBK537054Bacterial Sepsis - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK537054

   May 21, 2023 · Objectives: Review the pathophysiology of bacterial sepsis. Describe the typical lab findings in bacterial sepsis. Summarize the components of the acute sepsis bundle and the components of the sepsis management bundle used in the evaluation and treatment of patients with sepsis.

   • Author: Benjamin Bullock, Michael D. Benham
   • Published: 2023/05/21

   • Affiliations: Baylor Scott & White, Baylor Scott and White

6. www.nigms.nih.gov › fact-sheets › PagesSepsis - National Institute of General Medical Sciences

   www.nigms.nih.gov › fact-sheets › Pages

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   Jan 3, 2024 · Sepsis is a person’s overwhelming or impaired whole-body immune response to an insult —an infection or an injury to the body, or something else that provokes such a response. Sepsis occurs unpredictably and can progress rapidly. In the worst cases, blood pressure drops, the heart weakens, and the patient spirals toward septic shock.

7. www.who.int › news › itemGuidelines on the Clinical Management of Sepsis

   www.who.int › news › item

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   Jan 30, 2024 · Reading time: 2 min (601 words) Sepsis is the most common serious complication of infection. It affects people worldwide, but has a particularly high burden in low- and middle-income countries where resources to treat it are more limited. Estimates from 2017 suggest 48.9 million cases of sepsis occur each year, with 11 million deaths.

8. www.aafp.org › pubs › afpSepsis: Diagnosis and Management | AAFP

   www.aafp.org › pubs › afp

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   Apr 1, 2020 · The guidelines define septic shock as sepsis with circulatory, cellular, and metabolic dysfunction that is associated with a higher risk of mortality; the presence of hypotension is no longer...