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1. ashpublications.org › blood › articleHow I treat autoimmune hemolytic anemia | Blood | American ...

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   Jun 1, 2017 · Here is a primer for the clinician to aid in the fundamental understanding of immune mediators in AIHA, diagnosis, and prognostic risk. Advances in understanding the pathophysiology of AIHA and how to use anti–CD20 antibodies with or without immunosuppressive agents has augmented treatment approaches.

2. ashpublications.org › Autoimmune-hemolytic-anemiaAutoimmune hemolytic anemia | Hematology, ASH Education ...

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   Nov 30, 2018 · Autoimmune hemolytic anemia (AIHA) is a decompensated acquired hemolysis caused by the host’s immune system acting against its own red cell antigens. Consequent complement activation can impact the clinical picture and is an emerging target for therapeutic approaches.

   • Author: Anita Hill, Quentin A. Hill

   • Publish Year: 2015

3. ashpublications.org › hematology › articleWarm autoimmune hemolytic anemia and the best treatment ...

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   Dec 9, 2022 · Warm autoimmune hemolytic anemia (wAIHA) is characterized by evidence of red blood cell (RBC) hemolysis and a direct antiglobulin test positive for IgG and sometimes complement.

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5. www.nejm.org › doi › fullAutoimmune Hemolytic Anemias | New England Journal of Medicine

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   Oct 6, 2021 · Autoimmune hemolytic anemia (AIHA) is defined as increased destruction of red cells through autoimmune mechanisms, usually mediated by autoantibodies against erythrocyte surface antigens....

   • Author: Sigbjørn Berentsen, Wilma Barcellini

   • Publish Year: 2021

6. www.ncbi.nlm.nih.gov › pmc › articlesAutoimmune hemolytic anemia: current knowledge and ...

   www.ncbi.nlm.nih.gov › pmc › articles

   Nov 20, 2020 · The pathogenesis of AIHA is complex and still not fully understood. Recent studies indicate the involvement of T and B cell dysregulation, reduced CD4+ and CD25+ Tregs, increased clonal expansions of CD8 + T cells, imbalance of Th17/Tregs and Tfh/Tfr, and impaired lymphocyte apoptosis.

   • Author: Sylwia Sulimiera Michalak, Anna Olewicz-Gawlik, Anna Olewicz-Gawlik, Joanna Rupa-Matysek, Edyta Woln...
   • DOI: 10.1186/s12979-020-00208-7

   • Publish Year: 2020
   • Publication: Immun Ageing. 2020; 17: 38.

7. my.clevelandclinic.org › health › diseasesAutoimmune Hemolytic Anemia: Treatment, Symptoms & Types

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   What causes autoimmune hemolytic anemia? In approximately half of all cases, autoimmune hemolytic anemia causes are unknown (idiopathic autoimmune hemolytic anemia). In other cases, there’s a link between AIHA and other disorders.

8. People also ask

   What is hereditary spherocytosis?

   • Hereditary spherocytosis (chronic familial icterus; congenital hemolytic jaundice; familial spherocytosis; spherocytic anemia) is an autosomal dominant disease with variable gene penetrance due to mutations in spectrin, ankyrin, band 3, or protein 4.2. Approximately 25% of cases are sporadic.

   Hereditary Spherocytosis and Hereditary Elliptocytosis

   www.merckmanuals.com/professional/hematology-and-oncology/anemias-caused-by-hemolysis/hereditary-spherocytosis-and-hereditary-elliptocytosis

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   What is autoimmune hemolytic anemia?

   • A note from Cleveland Clinic Autoimmune hemolytic anemia happens when your immune system attacks your red blood cells. Symptoms may be mild or severe and can be treated using a number of different methods. While AIHA is highly treatable, it can be serious — and even fatal — if left unaddressed.

   Autoimmune Hemolytic Anemia: Treatment, Symptoms & Types - Clevel…

   my.clevelandclinic.org/health/diseases/22349-autoimmune-hemolytic-anemia

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   What is familial spherocytosis?

   • (See also Overview of Hemolytic Anemia.) Hereditary spherocytosis (chronic familial icterus; congenital hemolytic jaundice; familial spherocytosis; spherocytic anemia) is an autosomal dominant disease with variable gene penetrance due to mutations in spectrin, ankyrin, band 3, or protein 4.2.

   Hereditary Spherocytosis and Hereditary Elliptocytosis

   www.merckmanuals.com/professional/hematology-and-oncology/anemias-caused-by-hemolysis/hereditary-spherocytosis-and-hereditary-elliptocytosis

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   What is warm autoimmune hemolytic anemia?

   • Hematology Am Soc Hematol Educ Program (2022) 2022 (1): 105–113. Warm autoimmune hemolytic anemia (wAIHA) is characterized by evidence of red blood cell (RBC) hemolysis and a direct antiglobulin test positive for IgG and sometimes complement.

   Warm autoimmune hemolytic anemia and the best treatment strategies

   ashpublications.org/hematology/article/2022/1/105/493508/Warm-autoimmune-hemolytic-anemia-and-the-best

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9. www.merckmanuals.com › professional › hematology-andHereditary Spherocytosis and Hereditary Elliptocytosis

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   Hereditary spherocytosis and hereditary elliptocytosis are congenital red blood cell (RBC) membrane disorders that can cause a mild hemolytic anemia. Symptoms, generally milder in hereditary elliptocytosis, include variable degrees of anemia, jaundice, and splenomegaly.