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  1. London WC. / 51.518; -0.122. The WC (Western Central) postcode area, also known as the London WC postcode area, [2] is a group of postcode districts in central London, England. The area covered is of high density development, and includes parts of the City of Westminster and the London Boroughs of Camden and Islington, plus a very small part of ...

  2. Dec 25, 2001 · WC1 and WC2 proteins are found in the nucleus in the dark and after light induction. Western blots show WC1 (upper panel) and WC2 proteins (lower panel) in nuclear and cytoplasmic fractions prepared from mycelia before and after different times of illumination. Unspecific cross-reactions are indicated by asterisks.

    • Carsten Schwerdtfeger, Hartmut Linden
    • 94
    • 2000
    • 25 December 2001
  3. Jun 30, 2023 · Both WCC subunits, WC1 and WC2, coprecipitated with 2xV5-HDA3 in samples from dark-grown and LP-exposed samples (Fig. 5E and fig. S4A). In contrast, neither WC1 nor WC2 coprecipitated with V5 antibody from extract prepared from a WT control strain, expressing untagged HDA3. The data indicate that HDA3 is a constitutive interactor of WCC.

  4. Mar 30, 2015 · Light is an important environmental cue that affects physiology and development of Neurospora crassa. The light-sensing transcription factor (TF) WCC, which consists of the GATA-family TFs WC1 and WC2, is required for light-dependent transcription. SUB1, another GATA-family TF, is not a photoreceptor but has also been implicated in light ...

  5. Feb 23, 2023 · The activities of WC1 and WC2 In the photorepair of UVB-induced CPD and 6-4PP DNA lesions were previously shown to elucidate the high photoreactivation activities of Rad1 and Rad10 in the two insect mycopathogens [52,53,54]. Interestingly, the links of WC1 and WC2 to Phr1, Phr2, Rad1, and Rad10 are somewhat different between the two fungi.

    • 10.3390/jof9030290
    • 2023/03
    • J Fungi (Basel). 2023 Mar; 9(3): 290.
  6. Also, each has a PAS domain (17, 18) similar to that in the clock geneper and found in photoreceptor molecules from both prokaryotes and eukaryotes (18, 21, 22). WC-1 and WC-2 are thought to be the transcription factors required for the induction of all light-regulatable promoters in Neurospora ( 17 , 18 ) but had not been expected to have ...

    • Susan K. Crosthwaite, Jay C. Dunlap, Jennifer J. Loros
    • 1997
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  8. Here, we present a biochemical analysis of WC1 and WC2 polypeptides in N. crassa. Using specific antisera against WC1 and WC2, respectively, the subcellular localization of the WC polypeptides was investigated. The WC1 protein was localized exclusively in the nucleus, whereas WC2 was detected in both the nuclear and cytoplasmic fractions.

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