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      • Once infected with the Borrelia burgdorferi bacterium, your child may display a range of nonspecific symptoms that mimic other conditions. Symptoms can also change over time, making diagnosis more challenging. If left untreated, the infection can spread to other parts of the body, potentially causing long-term medical issues and permanent damage.
      www.chop.edu › conditions-diseases › lyme-disease-children
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  2. The main symptom is often a rash, but more than 1 in 5 people infected with Lyme don’t have the rash. In the earliest stage, diagnosis is usually based on symptoms and a history of a tick bite. In later stages, blood testing is very important to make a diagnosis of Lyme disease.

  3. Jul 29, 2019 · By Perri Klass, M.D. July 29, 2019. Lyme disease is on the rise. The 30,000 cases reported annually to the Centers for Disease Control and Prevention by state health departments represent only...

  4. For this reason, early diagnosis of Lyme disease is often based solely on the observation of the classic Lyme disease “bull’s-eye” rash, which develops in 70 to 80 percent of infected individuals. Other tests may be needed if the Lyme disease infection has spread beyond the skin, such as:

  5. Lyme disease can be difficult to diagnose because early symptoms of fever, severe fatigue, and achiness are also common in many other illnesses. In addition, diagnostic blood tests are not always dependable, particularly in early disease.

  6. Aug 18, 2021 · Given the many outstanding questions raised into the diagnosis, clinical presentation and treatment of Lyme disease, and the underlying molecular mechanisms that trigger persistent disease, there is an urgent need for more support.

    • Jason R. Bobe, Brandon L. Jutras, Elizabeth J. Horn, Monica E. Embers, Allison Bailey, Robert L. Mor...
    • 2021
  7. May 15, 2024 · Key points. Healthcare providers consider multiple factors when evaluating a patient for Lyme disease. Laboratory diagnosis of Lyme disease relies on a blood test that detects antibodies to the Lyme bacteria. It can take several weeks after infection for the immune system to make enough antibodies to be detected by the test.

  8. The disease can be challenging to diagnose because the acute presentation often resembles a flu-like illness and symptoms can be nonspecific. Lyme disease symptoms can be distinguished from other illnesses, in that symptoms can change, wax and wane in severity or come and go over time. [1]

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