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  2. Dec 5, 2019 · The European Society of Cardiology, currently endorsed by the American College of Cardiology, recommends the use of colchicine for both acute and recurrent episodes of pericarditis, and is supported by a series of trials and robust evidence.

  3. Colchicine works by decreasing swelling and lessening the build up of uric acid crystals that cause pain in the affected joint (s).This medication is also used to prevent attacks of pain in the abdomen, chest, or joints caused by a certain inherited disease (familial Mediterranean fever).

  4. Feb 29, 2024 · In healthy individuals, the pericardial cavity contains 15 to 50 mL of an ultrafiltrate of plasma. Diseases of the pericardium present clinically in one of several ways: Acute and recurrent pericarditis. Pericardial effusion without major hemodynamic compromise. Cardiac tamponade.

    • Diagnosis
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    • Preparing For Your Appointment

    To diagnose pericarditis, a healthcare professional examines you and asks questions about your symptoms and medical history. The care professional listens to your heart using a device called a stethoscope. Pericarditis causes a specific sound, called a pericardial rub. The noise occurs when the two layers of the sac surrounding the heart, called th...

    Treatment for pericarditis depends on the cause of the symptoms and how serious they are. Mild pericarditis may get better without treatment.

    Explore Mayo Clinic studiestesting new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition.

    Lifestyle and home remedies for mild pericarditis include rest and pain medicines sold without a prescription. If your healthcare professional recommends pain medicines, take them as directed. While you recover, do not take part in strenuous physical activity and competitive sports. Such activity can trigger pericarditis symptoms. Ask your healthca...

    You're likely to start by seeing a primary care professional or an emergency room doctor. You may be referred to a doctor trained in heart diseases. This type of care professional is called a cardiologist. Here's some information to help you prepare for your appointment.

  5. Sep 13, 2017 · Colchicine use is a first-line therapy for acute pericarditis as an adjunct to aspirin/NSAIDs therapy for three months. Corticosteroids are not recommended as first-line therapy for acute pericarditis as they appear to encourage recurrences.

  6. Dec 29, 2021 · It is considered standard-of-care therapy for pericarditis, and several clinical trials have evaluated its role in postoperative and postablation atrial fibrillation, postpericardiotomy syndrome, coronary artery disease, percutaneous coronary interventions, and cerebrovascular disease.

  7. Jan 7, 2020 · Acute pericarditis should be treated with a nonsteroidal anti-inflammatory drug (NSAID), typically with a 2- to 4-week taper after the resolution of symptoms. In addition, a 3-month course of colchicine (with weight-adjusted dosing) is recommended to reduce the risk of recurrent pericarditis.

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