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Abstract. Waardenburg syndrome (WS), also known as auditory-pigmentary syndrome, is the most common cause of syndromic hearing loss (HL), which accounts for approximately 2–5% of all patients ...
- Sida Huang, Jian Song, Chufeng He, Xinzhang Cai, Kai Yuan, Lingyun Mei, Yong Feng, Yong Feng
- 2021
Dec 9, 2020 · Introduction. Waardenburg syndrome (WS) is a single-gene disorder characterized by congenital onset sensorineural hearing loss, focal skin pigmentation abnormality (white forelock and focal depigmented skin), blue iris with or without heterochromia, and other abnormalities of neural crest-derived cells (Nayak and Isaacson, 2003; Van Camp and Smith, 2019).
Waardenburg syndrome (WS) is a genetic condition characterized by an association of sensorineural hearing impairment/loss and pigmentary abnormalities of the hair, eyes, and skin. The pigmentary abnormalities are usually congenital but some may result from early depigmentation [ 1 ].
- 10.3390/audiolres14010002
- 2024/02
- Audiol Res. 2024 Feb; 14(1): 9-25.
Sep 29, 2021 · Abstract. Waardenburg syndrome is a genetic disorder, resulting in defective control of the division and migration of neural crest cells including the melanocyte lineage during embryonic development. Primary involvement of melanocytes results in the characteristic phenotypic involvement including a white forelock, vitiligo, and heterochromia.
- Miranda Holbrook, Joseph D. Tobias
- 2021
Jul 1, 2017 · Waardenburg syndrome (WS) is a neurocristopathy with an autosomal dominant mode of inheritance, and considerable clinical and genetic heterogeneity. WS type II is the most common type of WS in many populations presenting with sensorineural hearing impairment, heterochromia iridis, hypoplastic blue eye, and pigmentary abnormalities of the hair ...
- Nazanin Jalilian, Mohammad Amin Tabatabaiefar, Mahboubeh Yazdanpanah, Elham Darabi, Tayyeb Bahrami, ...
- 10.22088/IJMCM.BUMS.7.1.17
- 2018
- Int J Mol Cell Med. 2018 Winter; 7(1): 17-23.
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Dec 21, 2023 · Waardenburg syndrome (WS) is characterized by hearing loss and pigmentary abnormalities of the eyes, hair, and skin. The condition is genetically heterogeneous, and is classified into four clinical types differentiated by the presence of dystopia canthorum in type 1 and its absence in type 2. Additi …
Aug 15, 2022 · Waardenburg syndrome is a genetic condition that affects the coloring (pigmentation) of your skin, hair and eyes. This condition can also cause hearing loss. In rare cases, Waardenburg syndrome can cause constipation or intestinal blockages. Treatment is available to alleviate symptoms but isn’t necessary for all types of the condition.
