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  1. Sep 2, 2021 · The term “clinically significant” can be used for the researches in which clinically relevant results or outcomes are used to assess the effectiveness or efficacy of a treatment modality. When used the term “clinically significant” findings are those who make the patient improves the quality of life and makes him/her feel, function well.

  2. In medicine and psychology, clinical significance is the practical importance of a treatment effectwhether it has a real genuine, palpable, noticeable effect on daily life. [1]

  3. Nov 21, 2023 · Define clinical significance. Explore its purpose, history, and methods. Compare it to statistical significance and discuss an example of clinical significance.

  4. Feb 14, 2018 · Clinical relevance (also known as clinical significance) indicates whether the results of a study are meaningful or not for several stakeholders. 7 A clinically relevant intervention is the one whose effects are large enough to make the associated costs, inconveniences, and harms worthwhile. 8 Clinical relevance facilitates the understanding ...

  5. clinical significance. A change in a patients/subject's clinical status that is regarded as important, whether or not it is due to an intervention in the context of a clinical trial. The phrase clinical significance should not be used unless it is operationally defined. Segen's Medical Dictionary. © 2012 Farlex, Inc.

  6. Apr 19, 2018 · the extent to which a study result is judged to be meaningful in relation to the diagnosis or treatment of disorders. An example of a clinically significant result would be an outcome indicating that a new intervention strategy is effective in reducing symptoms of depression.

  7. Definition. Clinical significance is a perceived, valued, and functionally relevant discrepancy in symptoms/abilities that reflects an important change in functioning. This can involve either an improvement (usually as a result of treatment or intervention) or a decline (typically due progression of illness or disorder) as measured by symptoms ...

  8. Clinical significance, also called practical significance or clinical importance, attempts to answer whether a new finding will make a big enough difference to change the way a doctor treats a patient’s condition.

  9. Clinical significance or importance refers to the actual treatment effect that will determine whether the results of the trial or meta-analysis are likely to impact current medical practice (see the example in Fig. 2 ).

  10. Apr 1, 2001 · This article reviews the history of the clinical significance concept; describes the various methods for defining improvement, recovery, and clinically significant change; examines current criticisms of the methods; and describes the current use of the methods in practice.

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