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  1. In toxicology, the median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 is a toxic unit that measures the lethal dose of a given substance. The value of LD 50 for a substance is the dose required to kill half the members of a tested population after a specified test duration.

  2. Feb 11, 2018 · Median Lethal Dose Definition. The median lethal dose, or LD50, is a term used in toxicology as a measurement of a lethal dose of a substance (e.g., pathogen, medication, toxic substance, etc.). Specifically, the LD50 represents the dose at which a substance is lethal for 50% of tested subjects.

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  4. en.wikipedia.org › wiki › Lethal_doseLethal dose - Wikipedia

    The median lethal dose, LD 50 (abbreviation for "lethal dose, 50%"), LC 50 (lethal concentration, 50%) or LCt 50 (lethal concentration and time) of a toxin, radiation, or pathogen is the dose required to kill half the members of a tested population after a specified test duration.

  5. May 10, 2024 · LD stands for "Lethal Dose". LD 50 is the amount of a material, given all at once, which causes the death of 50% (one half) of a group of test animals. The LD 50 is one way to measure the short-term poisoning potential (acute toxicity) of a material. Toxicologists can use many kinds of animals but most often testing is done with rats and mice.

  6. Feb 28, 2024 · Infectious dose 50 (ID 50) refers to the dose or number of organisms that will infect 50% of an experimental group of hosts within a specified time. Lethal dose 50 (LD50) refers to the dose or number of organisms that will kill 50% of an experimental group of hosts within a specified time.

  7. Jun 20, 2014 · The median lethal dose of a substance, or the amount required to kill 50% of a given test population. LD50 is a measurement used in toxicology studies to determine the potential impact of toxic substances on different types of organisms. It provides an objective measure to compare and rank the toxicity of substances.

  8. Mar 9, 2021 · The dose of radiation expected to cause death to 50 percent of an exposed population within 30 days (LD 50/30). Typically, the LD 50/30 is in the range from 400 to 450 rem (4 to 5 sieverts) received over a very short period.

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