Search results
Immunoglobulins blood test
- An immunoglobulins blood test measures the amounts of IgM, IgG, and IgA in your blood to help diagnose different types of health conditions that may affect your immune system.
medlineplus.gov › lab-tests › immunoglobulins-blood-test
People also ask
What does a high Iga blood level mean?
What causes elevated IgA levels?
What does high Iga mean in blood?
What does a low IgA blood test mean?
Sep 19, 2023 · An immunoglobulin test measures the amount of antibodies in your blood or cerebrospinal fluid. Antibodies are proteins that fight off infections and allergies. Learn about the different types of immunoglobulins, why you might need this test, and what the results mean.
- What Is Iga?
- Normal IGA Levels by Age
- IGA Levels & Lifespan
- IGA Genetics
- GeneratedCaptionsTabForHeroSec
Definition
Immunoglobulin A (IgA) is a type of antibody. Antibodies are proteins of the immune system that bind to and neutralize pathogens such as bacteria and viruses . IgA is one of the five immunoglobulin classes (in addition to IgG, IgM, IgD, and IgE) . In the human body, more IgA is produced per day than all other antibodies combined [2, 3, 1]. IgA is produced by white blood cells (B cells) and is then transported into fluids secreted by mucosal cells. This IgA is called the secretory IgA. S...
Function
Mucosal barriers (where IgA is present) separate the interior of the body from the outside world. At these sites,IgA maintains a balanced immune response. It defends against harmful microbes but also prevents reactions against good bacteria and environmental proteins (such as food antigens) . IgA has many important functions: 1. It is the first line of defense against harmful microbes [1, 3]. 2. It removes microbes that have breached the epithelial barrier (such as the intestinal barrier)...
Normal IgA levels vary slightly depending on the laboratory used to test them. They gradually increase with age and weight in children until they reach stable levels in adults. Blood IgA levels are higher in males than in females . These are the approximate values for IgA depending on age: 1. 0-1 years: 1-83 mg/dL 2. 1-5 years: 20-152 mg/dL 3. 5-10...
Associations with Mortality
Both low and high IgA levels are associated with higher mortality. In 4,255 Vietnam-era war veterans, higher IgA levels were associated with a 2-fold increased risk of dying from both all-causes and infectious diseases . In people aged 90 – 99 years, higher IgA levels were associated with higher mortality . Similarly, in 8-year-olds, high IgA levels (>400 mg/dl) were associated with higher mortality. IgA levels were related to cancer mortality in males . On the other hand, higher...
If you’re not a big fan of genetics, skip straight to our other posts about IgA in the next section. The following genes have been associated with IgA levels and IgA deficiency:
IgA is a type of antibody that protects the body from infection and maintains immune tolerance. Learn what the IgA blood test can tell you about your health, how it varies by age and weight, and which genes are associated with IgA levels and deficiency.
Learn about IgA deficiency, a genetic condition that affects your immune system and can cause infections, allergies, and autoimmune diseases. Find out how it is diagnosed, treated, and prevented.
An immunoglobulins test usually measures three specific types of immunoglobulins. They are called igG, igM, and IgA. If your levels of igG, igM, or IgA are too low or too high, it may be a sign of a serious health problem. Other names: quantitative immunoglobulins, total immunoglobulins, IgG, IgM, IgA testing
This test measures the amount of immunoglobulins (antibodies) in your blood. It can help diagnose and monitor conditions that affect your immune system, such as infections, autoimmune disorders, or cancers.
Detection or monitoring of IgA monoclonal gammopathies and IgA-related immune deficiencies.
Nov 9, 2021 · This test measures the amount of immunoglobulins A, G, and M (IgA, IgG, IgM) in the blood and, in certain circumstances, in cerebrospinal fluid or saliva. It helps evaluate a person’s immune system status and detect and monitor immunoglobulin deficiency or excess.
