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  1. Caffeine is a CNS stimulant that is used with pain relievers to increase their effect. It has also been used for migraine headaches. However, caffeine can also cause physical dependence when it is used for a long time. This may lead to withdrawal (rebound) headaches when you stop taking it.

    • Proper Use

      Take this medicine only as directed by your doctor. Do not...

    • Precautions

      It is very important that your doctor check your progress...

    • Side Effects

      Along with its needed effects, a medicine may cause some...

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    • Beta-Blockers
    • Antiepileptics
    • Antidepressants

    Beta-blockers slow down your heart rate by blocking certain hormones. It’s unclearTrusted Sourceexactly how they work to prevent migraine. Examples include: 1. propranolol 2. timolol 3. bisoprolol 4. metoprolol 5. atenolol 6. nadolol

    Research shows that some antiepileptics may help prevent migraine. But it’s not fully understood howTrusted Source they do this. Topiramate and valproateare the medications with the most evidence for migraine prevention.

    Some antidepressantsmay also help prevent migraine. Experts are not sure why they prevent migraine. It may have to do with their effect on serotonin in your brain. The most common antidepressants doctors prescribe to treat migraine are amitriptylineand fluoxetine.

  3. Aug 27, 2021 · A variety of drugs used to treat headaches, such as Excedrin, Anacin, and Midol, contain caffeine. This is because caffeine may reduce the sensation of pain through its effects on...

  4. Jan 10, 2017 · For people who experience migraine, caffeine taken three or more days per week, for whatever reason, may lead to dependency and increased migraine frequency. For those who have frequent headaches, avoidance of all caffeine is ideal, and at least until improvement in headache frequency is seen.

  5. Sep 23, 2022 · An individual may take medications containing caffeine at the first sign of a migraine. However, it is important to speak with a doctor about the symptoms, particularly if someone does not...

  6. Mar 17, 2022 · Caffeine is a well-known and effective ingredient in many over-the-counter and prescription migraine medications. But it’s also one of the top foods to avoid if you live with migraine.

  7. Jul 28, 2020 · The aim of this review is to examine the relationship between caffeine and migraine, and to check whether caffeine is a migraine trigger and avoiding it may be of benefit to certain patients, and to find out if caffeine may be helpful in migraine treatment.

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