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  1. Sep 24, 2023 · Prophylactic antibiotics decrease your risk of developing infections that can sometimes be life-threatening. Prophylactic antibiotics can also stop a chronic or recurrent infection from coming back.

    • Overview
    • Drugs for antibiotic prophylaxis
    • Factors for use
    • How it’s given
    • Talk to your doctor

    About antibiotic prophylaxis

    Antibiotic prophylaxis is the use of antibiotics before surgery or a dental procedure to prevent a bacterial infection. This practice isn’t as widespread as it was even 10 years ago. This is due to:

    •the increase in the resistance of bacteria to antibiotics

    •the change in bacteria that cause infections

    •improvements in technology that can detect infections

    However, antibiotic prophylaxis is still used in people who have certain risk factors for bacterial infection. Professional guidelines recommend using antibiotics before procedures that have a high risk of bacterial infection. These include:

    The most common antibiotics used before surgeries are cephalosporins, such as cefazolin and cefuroxime. Your doctor may prescribe vancomycin if you are allergic to cephalosporins. They may also prescribe it if antibiotic resistance is a problem.

    For dental procedures, your doctor will likely prescribe amoxicillin or ampicillin.

    People who may need antibiotic prophylaxis usually have factors that put them at higher risk of infection during surgery than the general population. These factors include:

    •very young or very old age

    •poor nutrition

    •obesity

    •diabetes

    •smoking, including a history of smoking

    The drug forms and administration usually depend on the type of procedure you will have.

    Before surgery, a healthcare provider usually gives antibiotics through a tube that they have inserted into one of your veins. Or they may prescribe a pill. You usually take the pill about 20 minutes to an hour before your procedure. If the surgery involves your eyes, your doctor may give you drops or a paste. They will apply these directly to your eyes.

    Antibiotic prophylaxis is effective, but you should still watch for symptoms of infection after your procedure. These include fever as well as pain, tenderness, pus, or an abscess (pus-filled lump) near the surgical site. Untreated infections can lead to longer recovery times. In very rare cases, they can cause death. Call your doctor right away if...

  2. Prophylaxis is no longer recommended for uncomplicated gastrointestinal bronchoscopy without incision of the respiratory mucosa and for urinary procedures. If the urine is colonized or infected before an elective cystoscopy, antibiotic therapy to eradicate the infection before the urologic manipulation is recommended.

    • Mark J. Enzler, Elie Berbari, Douglas R. Osmon
    • 2000
  3. Jun 28, 2018 · At the time of UTI, 28 (14%) of 203 participants in the prophylaxis group reported ever having adverse events due to treatment antibiotics versus 60 (30%) of 201 participants in the no prophylaxis group—predominately nausea (20 [10%] of 203 vs 38 [19%] of 201), diarrhoea (13 [6%] of 203 vs 31 [15%] of 201), and candida infection (ten [5%] of ...

    • Holly Fisher, Yemi Oluboyede, Thomas Chadwick, Mohamed Abdel-Fattah, Catherine Brennand, Mandy Fader...
    • 2018
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  5. Jan 16, 2024 · If antibiotic prophylaxis is inadvertently not administered prior to the dental procedure, it may be administered up to two hours after the procedure . Adverse effects — Although antibiotic exposure is limited with antibiotic prophylaxis therapy, there is a risk of adverse effects. Use of antibiotic prophylaxis beyond the recommend clinical ...

  6. Antibiotic prophylaxis should be offered to all patients who are believed to have an increased risk of infection . High-risk situations include bites to body areas where deeper structures (tendons and bones) can become easily injured, puncture wounds (difficult to clean), bites in which treatment is delayed more than 8 to 10 hours, bites in ...

  7. Jul 1, 2013 · Antibiotic therapy for 60 days: ciprofloxacin (Cipro; 500 mg orally) twice daily or doxycycline (100 mg orally) twice daily or, for pregnant women or children, amoxicillin (500 mg orally) three ...

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