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- DictionarySe·nes·cence/səˈnes(ə)ns/
noun
- 1. the condition or process of deterioration with age.
Senescence (/ s ɪ ˈ n ɛ s ə n s /) or biological aging is the gradual deterioration of functional characteristics in living organisms. Whole organism senescence involves an increase in death rates or a decrease in fecundity with increasing age, at least in the later part of an organism's life cycle.
Learn the meaning of senescence, a word that can refer to the state of being old, the arrest of cell division, or the decline of plant growth. See examples, synonyms, etymology, and related words for senescence.
Jan 2, 2018 · Senescence is a cellular response characterized by a stable growth arrest and other phenotypic alterations that include a proinflammatory secretome. Senescence plays roles in normal development, maintains tissue homeostasis, and limits tumor progression. However, senescence has also been implicated as a major cause of age-related disease.
- Domhnall McHugh, Domhnall McHugh, Jesús Gil, Jesús Gil
- 10.1083/jcb.201708092
- 2018
- J Cell Biol. 2018 Jan 2; 217(1): 65-77.
Aug 16, 2024 · Senescence is the gradual decline in health and function associated with aging. Learn about cellular senescence, organismal senescence and how to prevent or delay the effects of senescence with healthy lifestyle habits.
Aug 3, 2022 · Cellular senescence is a ubiquitous process with roles in tissue remodelling, including wound repair and embryogenesis. However, prolonged senescence can be maladaptive, leading to cancer...
2 days ago · Senescence is the process by which cells irreversibly stop dividing and enter a state of permanent growth arrest without undergoing cell death. Senescence can be induced by unrepaired DNA...
Dec 16, 2020 · Cellular senescence occurs in response to many different triggers, including DNA damage, telomere dysfunction, oncogene activation and organelle stress, and has been linked to processes such as...
