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      • An increase in core body temperature is known to improve survival and resolve infections. While an increased body temperature subsequently leads to an increased metabolic cost, it is known that the survival benefits outweigh the metabolic cost associated with a fever.
      www.ncbi.nlm.nih.gov › books › NBK562334
  1. Jul 14, 2016 · A fever occurring in sepsis may be associated with a survival benefit. However, this is not the case for non-infective triggers.

    • Edward James Walter, Sameer Hanna-Jumma, Mike Carraretto, Lui Forni
    • 10.1186/s13054-016-1375-5
    • 2016
    • Crit Care. 2016; 20: 200.
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  3. Nov 23, 2020 · Observational trials in humans suggest a survival benefit from fever, and randomized trials published before COVID-19 do not support fever reduction in patients with infection. Like public health measures that seem burdensome and excessive, fevers involve costly trade-offs but they can prevent infection from getting out of control.

    • Sylwia Wrotek, Edmund K LeGrand, Artur Dzialuk, Joe Alcock
    • 10.1093/emph/eoaa044
    • 2021
    • Evol Med Public Health. 2021; 9(1): 26-35.
  4. Jan 1, 2021 · A mild fever appears to improve outcome; it appears to diminish viral replication by several mechanisms, and improve host defence mechanisms against the pathogen. At higher temperatures, the outcome worsens, suggesting that the risks of fever on the host outweigh the benefit.

    • Lucas Belon, Peter Skidmore, Rohan Mehra, Edward Walter
    • 10.12998/wjcc.v9.i2.296
    • 2021
    • 2021/01/01
  5. Sep 11, 2023 · Fevers ability to control infections comes from the few extra, but critical, degrees it adds to enhance existing locally generated heat to harm vulnerable growing pathogens. And fever also ...

  6. May 15, 2015 · The fever response is executed by integrated physiological and neuronal circuitry and confers a survival benefit during infection. In this Review, we discuss our current understanding of how...

    • Sharon S Evans, Elizabeth A Repasky, Daniel T Fisher
    • 2015
  7. Dec 10, 2023 · Fevers can arise as the body's defense system fights off an infection, but they can also be triggered by other things, including autoimmune diseases such as rheumatoid arthritis, or occur as a...

  8. Mar 15, 2022 · Fever: How it stimulates the immune system. Why fever can be your friend in times of illness. Researchers claim that fevers are more than just a symptom of illness or infection. They found...

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