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  1. Oct 7, 2022 · When you're drunk and high at the same time, you could be in for double trouble. Here's what you should know about how alcohol and cannabis interact.

  2. Oct 26, 2023 · You’ve probably consumed cannabis at least once or twice while drinking alcohol. But have you ever thought about what happens when you’re drunk and high simultaneously? In general, alcohol affects your central nervous system by changing how your neurons communicate.

  3. Aug 27, 2019 · Occasionally mixing alcohol and weed — also known as crossfading — likely won’t lead to major health problems. But there are a lot of variables to consider, including which one you use first ...

  4. Dec 29, 2016 · Alcohol affects your central nervous system by changing how your neurons communicate. It does this by suppressing the excitatory neurotransmitter glutamate, and increasing the inhibitory neurotransmitter GABA. For the user, that means you feel less, perceive less, and remember less while you drink. But weed works in a different way.

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  6. Jul 17, 2024 · However, when mixed together, alcohol and marijuana can create unpleasant side effects. Drinking alcohol before smoking marijuana increases the absorption of the mind-altering chemical tetrahydrocannabinol (THC) found in marijuana and can intensify the drug’s effects.

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