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    • Limited evidence of carcinogenicity in humans

      • IARC group 2B substances, mixtures and exposure circumstances are those that have been classified as "possibly carcinogenic to humans" by the International Agency for Research on Cancer (IARC) as This category is used when there is limited evidence of carcinogenicity in humans and less than sufficient evidence of carcinogenicity in experimental animals.
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  2. Dec 1, 2023 · See Preventable Exposures Associated With Human Cancers (Cogliano et al., 2011) Read the IARC Monographs Q&A for answers to commonly asked questions on the evaluation process.

  3. For example, IARC considers there to be strong evidence that both tobacco smoking and eating processed meat can cause cancer, so both are listed as “carcinogenic to humans.” But smoking is much more likely to cause cancer than eating processed meat, even though both are in the same category.

  4. IARC group 1 Carcinogens are substances, chemical mixtures, and exposure circumstances which have been classified as carcinogenic to humans by the International Agency for Research on Cancer (IARC). This category is used when there is sufficient evidence of carcinogenicity in humans.

  5. Agents are assigned to either Group 2A (probably carcinogenic to humans) or Group 2B ( possibly carcinogenic to humans ) on the basis of epidemiological and experimental evidence of carcinogenicity and mechanistic and other relevant data.

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  6. The IARC Monographs identify environmental factors that are carcinogenic hazards to humans. These include chemicals, complex mixtures, occupational exposures, physical agents, biological agents, and lifestyle factors.

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