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Allergic reaction
- Morbilliform drug eruption is a form of allergic reaction. It is mediated by cytotoxic T-cells and classified as a Type IV immune reaction. The target of attack may be drug, a metabolite of the drug, or a protein bonded to the drug. Inflammation follows the release of cytokines and other effector immune cells.
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What causes morbilliform drug eruption? Morbilliform drug eruption is a form of allergic reaction. It is mediated by cytotoxic T-cells and classified as a Type IV immune reaction. The target of attack may be drug, a metabolite of the drug, or a protein bonded to the drug.
Mar 13, 2019 · The term “morbilliform” connotes a measles-like: the rash of measles is classically described as having macules that are 3 to 4 mm in size that coalesce. MDE is usually itchy. The eruption usually begins on the trunk and upper extremities and progresses caudally.
Jan 12, 2023 · Exanthematous (maculopapular) drug eruption, also called morbilliform (measles-like) drug-induced exanthem, is the most common drug hypersensitivity reaction [ 1,2 ]. It is characterized by a disseminated, and occasionally generalized, symmetric eruption of erythematous macules and/or papules ( picture 1A-B) that occur approximately one to two ...
May 11, 2024 · Morbilliform drug reactions, a term derived from "morbilli," which means measles, describe a particular type of skin rash that can develop as an adverse reaction to certain medications. These rashes often resemble the rash associated with measles, with characteristic red spots that may be itchy and can spread across the body.
Mar 8, 2021 · Exanthematous drug eruption, also known as a morbilliform or maculopapular drug eruption, is the most common type of drug hypersensitivity reaction [1]. Diagnosis of exanthematous drug eruption should be suspected in a patient receiving drug treatment who presents with a new onset rash.
When they happen from drugs, they’re called “morbilliform drug eruptions.” How Common Is It? It’s hard to say exactly how common these rashes are since they have so many different causes. Many...
Morbilliform drug eruption is considered to be a type IVc hypersensitivity reaction and is caused by a wide variety of medications. Morbilliform drug eruption occurs in 1% to 5% of first-time drug users and is characterized by a widespread, maculopapular, symmetrically distributed rash.
