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Aug 2, 2022 · Now researchers at Tufts University and the University of Oxford, using a three-dimensional human tissue culture model mimicking the brain, report in the Journal of Alzheimer’s Disease that varicella zoster virus (VZV), which commonly causes chickenpox and shingles, may activate herpes simplex (HSV), another common virus, to set in motion the ...
Aug 2, 2022 · This study showed HSV-1 infection of human-induced neural stem cells (hiNSCs) caused changes that resembled changes observed in AD patients’ brains - amyloid plaque-like formations (PLFs), gliosis, neuroinflammation, and decreased functionality.
Jan 19, 2023 · Neuron. 2022 Jan 19 do: 10.1016/j.neuron.2022.12.029. Some viral illnesses may increase a person’s chances of later developing Alzheimer’s disease or another neurodegenerative disorder. Though a causal link cannot be confirmed, an NIH study found significant associations.
Jun 21, 2018 · Multiple viruses impact the biology of Alzheimer’s disease across domains such as DNA, RNA and proteins. Important roles for microbes and viruses in Alzheimer’s disease have been suggested and studied for decades, the authors noted. Since the 1980s, hundreds of reports have associated Alzheimer’s with bacteria and viruses.
Apr 4, 2021 · Alzheimer’s disease (AD) is characterized by the presence of β-amyloid plaques (Aβ) and neurofibrillary tangles (NFTs) in the brain. The prevalence of the disease is increasing and is expected to reach 141 million cases by 2050. Despite the risk factors associated with the disease, there is no known causative agent for AD.
- Ahmad Sait, Ahmad Sait, Cristian Angeli, Andrew J. Doig, Philip J. R. Day, Philip J. R. Day
- 10.1021/acschemneuro.0c00719
- 2021
- 2021/04/04
Jan 19, 2023 · Dementia was the brain malady most commonly associated with viral infections; it was linked with six different ones, including flu with or without pneumonia and viral encephalitis, a rare infection of the brain that can be caused by many different viruses.
Mar 2, 2023 · Neurodegenerative diseases, which include conditions such as Alzheimer disease (AD) Parkinson disease (PD), amyotrophic lateral sclerosis (ALS), vascular dementia and multiple sclerosis (MS), are...
