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   What is the best treatment for neonatal sepsis?

   • The most commonly recommended and used first-line treatment for both early and late onset neonatal sepsis is a beta-lactam antibiotic (most commonly ampicillin, flucloxacillin and penicillin) combined with an aminoglycoside (most commonly gentamicin) [ 21, 31, 48, 51, 54, 55, 56, 57 ].

   Antibiotic regimens for neonatal sepsis - a protocol for a systematic

   systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-019-1207-1

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   What is neonatal late onset sepsis?

   • Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality in the NICU and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration. Preter …

   Updates in Late-Onset Sepsis: Risk Assessment, Therapy, and Outcomes

   pubmed.ncbi.nlm.nih.gov/36316254/

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   Can antibiotic therapy prevent early onset sepsis in neonates?

   • Empirical use of antibiotic therapy in the prevention of early onset sepsis in neonates: a pilot study. Arch Med Sci. 2016;12 (3):603–13. Shane AL, Stoll BJ. Recent developments and current issues in the epidemiology, diagnosis, and management of bacterial and fungal neonatal sepsis. American Journal of Perinatology. 2013;30 (2):131–41.

   Antibiotic regimens for neonatal sepsis - a protocol for a systematic

   systematicreviewsjournal.biomedcentral.com/articles/10.1186/s13643-019-1207-1

   See all results for this question

2. publications.aap.org › neoreviews › articleUpdates in Late-Onset Sepsis: Risk Assessment, Therapy, and ...

   publications.aap.org › neoreviews › article

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   Nov 1, 2022 · Tools. Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality in the NICU and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration.

3. www.ncbi.nlm.nih.gov › books › NBK531478Neonatal Sepsis - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK531478

   Sep 29, 2022 · Objectives: Describe the etiology of early and late onset neonatal sepsis. Describe various clinical and laboratory findings associated with neonatal sepsis. Review the various treatment and management options available for neonatal sepsis.

   • Author: Meenakshi Singh, Mahdi Alsaleem, Cory P. Gray

   • Published: 2022/09/29

4. www.ncbi.nlm.nih.gov › pmc › articlesAntibiotic regimens for late‐onset neonatal sepsis - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   May 8, 2021 · Antibiotics have become the most used therapeutics in neonatal intensive care units, and observational studies in high‐income countries suggest that 83% to 94% of newborns treated with antibiotics for suspected sepsis have negative blood cultures. The last Cochrane Review was updated in 2005.

   • Author: Steven Kwasi Korang, Sanam Safi, Chiara Nava, Adrienne Gordon, Munish Gupta, Gorm Greisen, Ulrik Lau...
   • DOI: 10.1002/14651858.CD013836.pub2

   • Publish Year: 2021
   • Published: 2021

5. pubmed.ncbi.nlm.nih.gov › 36316254Updates in Late-Onset Sepsis: Risk Assessment, Therapy, and ...

   pubmed.ncbi.nlm.nih.gov › 36316254

   Nov 1, 2022 · Abstract. Neonatal late-onset sepsis (LOS) continues to threaten morbidity and mortality in the NICU and poses ongoing diagnostic and therapeutic challenges. Early recognition of clinical signs, rapid evaluation, and prompt initiation of treatment are critical to prevent life-threatening deterioration.

6. www.nature.com › articles › s41372/019/0577-5Standardizing the approach to late onset sepsis in neonates ...

   www.nature.com › articles › s41372/019/0577-5

   Jan 6, 2020 · Specific guidelines for neonates are often lacking and our NICU is not compliant with late onset sepsis (LOS) guidelines. Objective. By January 2019, there will be >75% compliance with our...

   • Author: V Lamba, S D'souza, C Carafa, A Zepf, C L Bassel, M Gutierrez, M Balakrishnan

   • Publish Year: 2020

7. Videos

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     41:49

     youtube.com

     NHSN Neonatal Component - Late Onset Sepsis and Meningitis Module (LOS/MEN) Overview

     Sep 10, 2021

     2.5K Views

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     17:56

     youtube.com

     Neonatal Sepsis: Early Onset vs Late Onset, Pathophysiology, Diagnosis and Treatment

     Oct 2, 2023

     298 Views

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     3:15

     youtube.com

     What's the recommended initial treatment for early onset neonatal sepsis? Empirical treatment of GBS

     Apr 3, 2020

     437 Views

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8. www.msdmanuals.com › neonatal-sepsisNeonatal Sepsis - Pediatrics - MSD Manual Professional Edition

   www.msdmanuals.com › neonatal-sepsis

   • Cached

   Late (after 3 days) Early-onset neonatal sepsis usually results from organisms acquired intrapartum. Most infants have symptoms within 6 hours of birth. Most cases are caused by group B streptococcus (GBS) and gram-negative enteric organisms (predominantly Escherichia coli).

9. systematicreviewsjournal.biomedcentral.comAntibiotic regimens for neonatal sepsis - a protocol for a ...

   systematicreviewsjournal.biomedcentral.com

   • Cached

   Dec 5, 2019 · Antibiotics are a central part of the first line treatment for sepsis in neonatal intensive care units worldwide. However, the evidence on the clinical effects of the commonly used antibiotic regimens for sepsis in neonates remains scarce. This systematic review aims to assess the efficacy and harms of antibiotic regimens for neonatal sepsis.